Gene Symbol | CCR10 |
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Entrez Gene | 2826 |
Alt Symbol | GPR2 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) receptor 10 |
Other Description | C-C CKR-10|C-C chemokine receptor type 10|CC chemokine receptor 10|CC-CKR-10|CCR-10|G protein-coupled receptor 2|G-protein coupled receptor 2 |
Swissprots | Q9NZG2 Q6T7X2 Q4V749 P46092 |
Accessions | AAA64593 EAW60866 P46092 AF208237 AAF72871 AF215981 AAF63709 AY429103 AAR07898 BC098132 AAH98132 BC098157 AAH98157 BC098304 AAH98304 BC099840 AAH99840 BM930170 CA423133 EU832758 ACE87769 GQ129298 ACT64432 NM_016602 NP_057686 |
Function | Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells. {ECO:0000269|PubMed:10781587}. |
Top Pathways | Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Chemokine signaling pathway |
CKR-10 (C-5) - sc-365531 from Santa Cruz Biotechnology
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CKR-10 (E-2) - sc-365957 from Santa Cruz Biotechnology
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CKR-10 (H-150) - sc-30035 from Santa Cruz Biotechnology
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CKR-10 (N-20) - sc-16995 from Santa Cruz Biotechnology
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Anti-GPR2/CCR10 antibody - ab3904 from Abcam
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Anti-GPR2/CCR10 antibody - ab30718 from Abcam
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Anti-GPR2/CCR10 antibody - ab13794 from Abcam
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Anti-CCR10 / GPR2 Antibody (C-Terminus) IHC-plus⢠- LS-A1155 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (aa350-362) IHC-plus⢠- LS-B2023 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody - LS-C48830 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (clone 248918, APC) - LS-C35337 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (aa4-31) - LS-C83956 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (aa1-30, AP) - LS-C253799 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (aa1-30, Biotin) - LS-C253801 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (aa9-31) - LS-C83955 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (aa1-30, APC) - LS-C253800 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (aa1-30, FITC) - LS-C253802 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (aa1-30, Azide-free, HRP) - LS-C253803 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (aa1-30, PE) - LS-C253804 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (aa1-30) - LS-C329335 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (aa1-30) - LS-C168489 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (aa143-192) - LS-C146448 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (aa4-31) - LS-C187705 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (aa9-31) - LS-C187843 from LifeSpan Bioscience
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Anti-CCR10 / GPR2 Antibody (N-Terminus) IHC-plus⢠- LS-A1153 from LifeSpan Bioscience
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