| Gene Symbol | Dido1 |
|---|---|
| Entrez Gene | 23856 |
| Alt Symbol | 6720461J16Rik, D130048F08Rik, DATF-1, DIO-1, Datf1 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | death inducer-obliterator 1 |
| Other Description | death inducer-obliterator-2|death inducer-obliterator-3|death-associated transcription factor 1|death-inducer obliterator 1 |
| Swissprots | Q3ZTP5 A2AJ48 Q6ZQD7 B2RS46 Q8C9B9 Q8CHR5 Q3ZTP6 Q9WV00 Q4V9W1 Q8BMD0 Q80V34 A2AJ47 Q8BRG2 Q05C59 |
| Accessions | EDL07346 EDL07347 Q8C9B9 AI465832 AJ238332 CAB48401 AK014422 AK031764 AK032843 BAC28053 AK042474 BAC31270 AK044919 BAC32141 AK049707 AK051291 AK051426 AK083334 AK086242 AK129117 BAC97927 AY425951 AAR84049 AY425952 AAR84050 BB736329 BC029110 AAH29110 BC039702 BC044755 AAH44755 BC060249 BC096662 AAH96662 BC138712 AAI38713 BC138713 AAI38714 BC145401 BY713603 XM_006500608 XP_006500671 XM_006500609 XP_006500672 XM_006500610 XP_006500673 XM_006500611 XP_006500674 XM_006500612 XP_006500675 XM_006500615 XP_006500678 XM_006500616 XP_006500679 NM_001291432 NP_001278361 NM_001291433 NP_001278362 NM_011805 NP_035935 NM_175551 NP_780760 NM_177852 NP_808520 NR_111965 |
| Function | Required for early embryonic stem cell development (By similarity). Putative transcription factor, weakly pro-apoptotic when overexpressed. {ECO:0000250}. |
| Subcellular Location | Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=Translocates to the mitotic spindle upon loss of interaction with H3K4me3 during early mitosis (By similarity). Translocates to the nucleus after pro-apoptotic stimuli. {ECO:0000250}. |
| Tissue Specificity | Ubiquitous. Expressed at intermediate levels. |
Dio-1 CRISPR/Cas9 KO Plasmid (m) - sc-423866 from Santa Cruz Biotechnology
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Dio-1 HDR Plasmid (m) - sc-423866-HDR from Santa Cruz Biotechnology
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Dio-1 Double Nickase Plasmid (m) - sc-423866-NIC from Santa Cruz Biotechnology
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Dio-1 Double Nickase Plasmid (m2) - sc-423866-NIC-2 from Santa Cruz Biotechnology
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Dio-1 CRISPR Activation Plasmid (m) - sc-423866-ACT from Santa Cruz Biotechnology
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Dio-1 CRISPR Activation Plasmid (m2) - sc-423866-ACT-2 from Santa Cruz Biotechnology
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Dio-1 Lentiviral Activation Particles (m) - sc-423866-LAC from Santa Cruz Biotechnology
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Dio-1 Lentiviral Activation Particles (m2) - sc-423866-LAC-2 from Santa Cruz Biotechnology
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Dio-1 siRNA (m) - sc-35195 from Santa Cruz Biotechnology
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Dio-1 shRNA Plasmid (m) - sc-35195-SH from Santa Cruz Biotechnology
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Dio-1 shRNA (m) Lentiviral Particles - sc-35195-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU048961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN29995 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND29995 from Sigma-Aldrich
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DIDO1 siRNA (Mouse) - CRM4552 from Cohesion Biosciences
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DIDO1 - MBS8224983 from MyBioSource
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shRNA set against Mouse DIDO1 (NM_175551.3) - SHH278069 from Creative biogene
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shRNA set against Mouse Dido1(NM_175551.3) - SHH005357 from Creative biogene
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shRNA set against Mouse Dido1(NM_011805.2) - SHH005375 from Creative biogene
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shRNA set against Mouse Dido1(NM_177852.3) - SHH005393 from Creative biogene
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DIDO1 shRNA Plasmid (Mouse) - CHM4552 from Cohesion Biosciences
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DIDO1 miRNA 3'UTR clone - MiUTR1M-03863 from Creative biogene
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DIDO1 miRNA 3'UTR clone - MiUTR1M-03864 from Creative biogene
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DIDO1 miRNA 3'UTR clone - MiUTR1M-03865 from Creative biogene
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