Gene Symbol |
TCF25
|
Entrez Gene |
22980
|
Alt Symbol |
FKSG26, Hulp1, NULP1, PRO2620, hKIAA1049
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
transcription factor 25 (basic helix-loop-helix)
|
Other Description |
NULP1|TCF-25|nuclear localized protein 1|transcription factor 25
|
Swissprots |
Q9UPV3 Q2MK75 Q9BQ70
|
Accessions |
EAW66677 EAW66678 EAW66679 Q9BQ70 AB028972 BAA83001 AF130092 AAG35518 AF322111 AAG50276 AK024679 BAB14959 AK095785 AK127949 AK301053 BAG62664 BC000959 AAH00959 BC009349 AAH09349 BC011884 AAH11884 BI913551 DQ321703 ABC55265 EU446609 ABZ92138 XM_005256297 XP_005256354 XM_005256298 XP_005256355 XM_005256299 XP_005256356 XM_011522956 XP_011521258 XM_011522957 XP_011521259 XM_011522958 XP_011521260 XM_011522959 XP_011521261 XM_011522960 XP_011521262 XM_011522961 XP_011521263 NM_014972 NP_055787
|
Function |
May play a role in cell death control. Acts as a transcriptional repressor. Has been shown to repress transcription of SRF in vitro and so may play a role in heart development. {ECO:0000269|PubMed:16574069}.
|
Subcellular Location |
Nucleus {ECO:0000269|PubMed:16574069, ECO:0000269|PubMed:18068114}. Note=Some staining in the cytosol.
|
Tissue Specificity |
In the embryo, widely expressed with highest levels in brain. In the adult, highest expression is found in the heart. {ECO:0000269|PubMed:16574069}.
|