| Gene Symbol |
IL4
|
| Entrez Gene |
3565
|
| Alt Symbol |
BCGF-1, BCGF1, BSF-1, BSF1, IL-4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
interleukin 4
|
| Other Description |
B cell growth factor 1|B_cell stimulatory factor 1|binetrakin|interleukin 4 variant 2|interleukin-4|lymphocyte stimulatory factor 1|pitrakinra
|
| Swissprots |
Q14630 Q6NZ77 P05112
|
| Accessions |
AAA59150 AAK71324 ADD60204 ADN03408 ADN03409 ADN03410 ADN03411 ADN03412 ADN03413 ADN03414 ADN03415 ADN03416 ADN03417 ADN03418 ADN03419 ADN03420 ADN03421 ADN03422 ADN03423 CAA29925 CAJ75955 CAV32874 CBL86566 CBX32734 EAW62322 EAW62323 P05112 AB102862 BAD89396 AF043336 AAC03537 AM937235 CAP72493 BC066277 AAH66277 BC066278 BC067514 AAH67514 BC067515 AAH67515 BC070123 AAH70123 CD640452 EF173851 ABM53124 JX878389 AGM38212 M13982 AAA59149 X81851 CAA57444 NM_000589 NP_000580 NM_172348 NP_758858
|
| Function |
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
|
| Subcellular Location |
Secreted.
|
| Top Pathways |
Inflammatory bowel disease (IBD), Measles, PI3K-Akt signaling pathway, Leishmaniasis, Cytokine-cytokine receptor interaction
|
