Gene Symbol | TGOLN2 |
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Entrez Gene | 10618 |
Alt Symbol | TGN38, TGN46, TGN48, TGN51, TTGN2 |
Species | Human |
Gene Type | protein-coding |
Description | trans-golgi network protein 2 |
Other Description | TGN38 homolog|trans-Golgi network integral membrane protein 2|trans-Golgi network protein (46, 48, 51kD isoforms)|trans-Golgi network protein TGN51 |
Swissprots | Q96QL2 Q53G68 D6W5K3 Q6ZTM7 O43500 Q8N6T8 O43492 O15282 Q53GV2 F8WBK2 B2R686 O43499 B8ZZ88 Q92760 O43501 O43493 Q6MZV1 |
Accessions | AAB96906 AAB96907 AAB96908 AAY24095 EAW99535 EAW99536 EAW99537 EAW99538 EAW99539 EAW99540 O43493 AA723637 AA814306 AF027515 AAC39541 AF027516 AAC39542 AK025557 AK126465 BAC86559 AK222829 BAD96549 AK223063 BAD96783 AK312479 BAG35383 AL133437 AL710137 AW630597 BC008461 AAH08461 BC028219 AAH28219 BC035237 BC046196 BC062782 BF515968 BP212295 BQ018277 BQ223385 BQ226188 BU192601 BX640733 BX640868 CAE45926 BY798185 CB216875 CD370267 CD518854 CD671318 EU176441 ABW03892 EU176775 ABW03576 U62390 AAC39539 X94333 CAA64002 NM_001206840 NP_001193769 NM_001206841 NP_001193770 NM_001206844 NP_001193773 NM_006464 NP_006455 |
Function | May be involved in regulating membrane traffic to and from trans-Golgi network. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single- pass type I membrane protein. Note=Primarily in trans-Golgi network. Cycles between the trans-Golgi network and the cell surface returning via endosomes. |
Tissue Specificity | Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells. |
TGN38 CRISPR/Cas9 KO Plasmid (h) - sc-401763 from Santa Cruz Biotechnology
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TGN38 HDR Plasmid (h) - sc-401763-HDR from Santa Cruz Biotechnology
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TGN38 Double Nickase Plasmid (h) - sc-401763-NIC from Santa Cruz Biotechnology
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TGN38 Double Nickase Plasmid (h2) - sc-401763-NIC-2 from Santa Cruz Biotechnology
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TGN38 CRISPR Activation Plasmid (h) - sc-401763-ACT from Santa Cruz Biotechnology
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TGN38 CRISPR Activation Plasmid (h2) - sc-401763-ACT-2 from Santa Cruz Biotechnology
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TGN38 Lentiviral Activation Particles (h) - sc-401763-LAC from Santa Cruz Biotechnology
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TGN38 Lentiviral Activation Particles (h2) - sc-401763-LAC-2 from Santa Cruz Biotechnology
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TGN38 siRNA (h) - sc-44148 from Santa Cruz Biotechnology
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TGN38 shRNA Plasmid (h) - sc-44148-SH from Santa Cruz Biotechnology
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TGN38 shRNA (h) Lentiviral Particles - sc-44148-V from Santa Cruz Biotechnology
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TGN46 RNAi - H00010618-R01 from Novus Biologicals
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MISSION® esiRNA - EHU005471 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21287 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21287 from Sigma-Aldrich
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TGOLN2 siRNA (Human) - CRH7231 from Cohesion Biosciences
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TGOLN2 - MBS828232 from MyBioSource
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shRNA set against Human TGOLN2 (NM_006464.3) - SHH426604 from Creative biogene
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Human TGN46 siRNA - orb267733 from Biorbyt
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TGOLN2 shRNA Plasmid (Human) - CHH7231 from Cohesion Biosciences
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TGOLN2 miRNA 3'UTR clone - MiUTR4H-TG08937 from Creative biogene
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