Gene Symbol | SLC25A37 |
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Entrez Gene | 51312 |
Alt Symbol | HT015, MFRN, MFRN1, MSC, MSCP, PRO1278, PRO1584, PRO2217 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 25 (mitochondrial iron transporter), member 37 |
Other Description | mitochondrial iron transporter 1|mitochondrial solute carrier protein|mitoferrin|mitoferrin-1|predicted protein of HQ2217|solute carrier family 25, member 37 |
Swissprots | Q9NYZ2 Q53FT7 A2RU93 Q9P0J2 Q969S1 Q69YJ8 |
Accessions | CAF86924 EAW63614 EAW63615 EAW63617 Q9NYZ2 AF113696 AF116630 AAF71053 AF116640 AAF71063 AF155660 AAF67479 AF223466 AAF64141 AF495725 AAQ06679 AK074708 AK075313 AK093931 AK127666 AK223194 BAD96914 AK314731 BAG37273 AL833186 CAH10415 AY032628 AAK38154 BC015013 AAH15013 BC033834 BC042973 BC062364 BC132799 AAI32800 BC132801 AAI32802 BI460337 BM926580 BX647289 HQ258387 ADR83141 S94541 AAD14436 XM_005273526 XP_005273583 XM_006716352 XP_006716415 XM_011544550 XP_011542852 XM_011544551 XP_011542853 XM_011544552 XP_011542854 XM_011544553 XP_011542855 XM_011544554 XP_011542856 NM_016612 NP_057696 |
Function | Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Mitoferrin CRISPR/Cas9 KO Plasmid (h) - sc-412181 from Santa Cruz Biotechnology
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Mitoferrin HDR Plasmid (h) - sc-412181-HDR from Santa Cruz Biotechnology
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Mitoferrin Double Nickase Plasmid (h) - sc-412181-NIC from Santa Cruz Biotechnology
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Mitoferrin Double Nickase Plasmid (h2) - sc-412181-NIC-2 from Santa Cruz Biotechnology
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Mitoferrin CRISPR Activation Plasmid (h) - sc-412181-ACT from Santa Cruz Biotechnology
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Mitoferrin CRISPR Activation Plasmid (h2) - sc-412181-ACT-2 from Santa Cruz Biotechnology
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Mitoferrin Lentiviral Activation Particles (h) - sc-412181-LAC from Santa Cruz Biotechnology
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Mitoferrin Lentiviral Activation Particles (h2) - sc-412181-LAC-2 from Santa Cruz Biotechnology
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Mitoferrin siRNA (h) - sc-77851 from Santa Cruz Biotechnology
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Mitoferrin shRNA Plasmid (h) - sc-77851-SH from Santa Cruz Biotechnology
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Mitoferrin shRNA (h) Lentiviral Particles - sc-77851-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU016661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19507 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19507 from Sigma-Aldrich
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SLC25A37 siRNA (Human) - CRH9689 from Cohesion Biosciences
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SLC25A37 - MBS8223868 from MyBioSource
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shRNA set against Human SLC25A37 (NM_016612.2) - SHH409740 from Creative biogene
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shRNA set against Human SLC25A37(NM_016612.2) - SHH221676 from Creative biogene
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Human SLC25A37 siRNA - orb270191 from Biorbyt
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SLC25A37 shRNA Plasmid (Human) - CHH9689 from Cohesion Biosciences
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SLC25A37 miRNA 3'UTR clone - MiUTR1H-09486 from Creative biogene
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