CSNK2A1

Gene Symbol	CSNK2A1
Entrez Gene	1457
Alt Symbol	CK2A1, CKII, CSNK2A3
Species	Human
Gene Type	protein-coding
Description	casein kinase 2, alpha 1 polypeptide
Other Description	CK II alpha 3|CK2 catalytic subunit alpha|casein kinase II alpha 1 polypeptide pseudogene|casein kinase II alpha 1 subunit|casein kinase II subunit alpha|protein kinase CK2
Swissprots	P20426 D3DVV8 P19138 Q14013 Q5U065 P68400 B4DYS6
Accessions	EAX10665 EAX10666 EAX10667 EAX10668 EAX10669 P68400 Q8NEV1 AB451279 BAG70093 AB451411 BAG70225 AK302583 BAG63838 AK312535 BAG35434 AU130091 AU131227 AU132198 AU133318 AW876962 AY735339 BC002615 BC011668 AAH11668 BC050036 AAH50036 BC053532 AAH53532 BC071167 AAH71167 BT019792 AAV38595 DQ354583 ABC86794 DQ893102 ABM84028 DQ896374 ABM87373 J02853 AAA56821 M55265 AAA35503 S53149 ABB72474 XM_011529175 XP_011527477 XM_011529176 XP_011527478 NM_001895 NP_001886 NM_177559 NP_808227 NM_177560 NP_808228
Function	Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation. Can also negatively regulate apoptosis. Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3. Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activat
Top Pathways	Wnt signaling pathway, Adherens junction, Tight junction, Ribosome biogenesis in eukaryotes, Measles

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active corn CKII alpha full length protein - ab90272 from Abcam Category Protein Prices $302.00 Sizes 10 µg Source E. coli Species Corn

Active human CKII alpha full length protein - ab60763 from Abcam Category Protein Prices $294.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Active human CKII alpha full length protein - ab90745 from Abcam Category Protein Prices $321.00 Sizes 10 µg Source E. coli Species Human

CKII alpha peptide - ab203372 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human CKII alpha full length protein - ab85981 from Abcam Category Protein Source E. coli Species Human

CSNK2A1 Antibody Blocking Peptide - LS-E18660 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CSNK2A1 Antibody Blocking Peptide - LS-E9529 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Casein Kinase 2 alpha Partial Recombinant Protein - H00001457-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Casein Kinase 2 alpha Recombinant Protein - H00001457-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Casein Kinase 2 alpha Protein - NBC1-18386 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Source E.coli Species Human

Casein Kinase 2 alpha Recombinant Protein - P4221 from Novus Biologicals Category Protein Prices $549.00 Sizes 5 µg Species Human

Casein Kinase 2 alpha Recombinant Protein - P4667 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 100 µg Species Human

Recombinant Casein Kinase 2 alpha Protein - NBP1-99933 from Novus Biologicals Category Protein Prices $295.00 Sizes 5 µg Source Baculovirus (Sf9 insect cells)

Recombinant Human Casein Kinase 2 alpha Protein - NBP1-99066 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Casein Kinase 2 alpha Peptide - P3169 from Novus Biologicals Category Peptide Species Human

CKII-alpha-CSNK2A1-Antibody-Center-Blocking-peptide - BP8144c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Casein Kinase 2 alpha (active) recombinant protein - GTX65062 from GeneTex Category Protein Prices $329.00 Sizes 5 μg Source Baculovirus (Sf9 insect cells) Species Human

CSNK2A1 Protein (OPPA01122) - OPPA01122 from Aviva Systems Biology Category Protein Prices $720.00 Sizes 3 µg Source E. Coli

CSNK2A1 Protein (OPPA01138) - OPPA01138 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human CSNK2A2 protein - orb244787 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human CSNK2A1 GST tag protein - orb84043 from Biorbyt Category Protein Prices $434.00, $612.00 Sizes 50 μg, 100 μg Source Insect Species Human

Human CSNK2A1 protein - orb244138 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

CSNK2A1, Human Casein Kinase alpha protein - orb80789 from Biorbyt Category Protein Prices $451.00, $774.00 Sizes 3 μg, 10 μg Source E.coli

Human CSNK2A1 protein (His Tag) - orb80790 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

CK2a1 protein - 30R-2852 from Fitzgerald Category Protein Prices $425.00 Sizes 5 µg Source Sf-9 insect cells Species Human

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