| Gene Symbol |
CD38
|
| Entrez Gene |
100009409
|
| Alt Symbol |
ADPRC 1
|
| Species |
Rabbit
|
| Gene Type |
protein-coding
|
| Description |
CD38 molecule
|
| Other Description |
2'-phospho-ADP-ribosyl cyclase|2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase|2'-phospho-cyclic-ADP-ribose transferase|ADP-ribosyl cyclase 1|ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1|CD38/ADP-ribosyl cyclase|cADPr hydrolase 1|cyclic ADP-ribose hydrolase 1
|
| Swissprots |
Q9MZ03
|
| Accessions |
Q9MZ03 AF272974 AAF87715 XM_008274039 XP_008272261 XM_008274042 XP_008272264 NM_001082683 NP_001076152
|
| Function |
Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. {ECO:0000269|PubMed:10477767, ECO:0000269|PubMed:10891341}.
|
| Subcellular Location |
Cell membrane; Single-pass type II membrane protein. Microsome membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein.
|
| Tissue Specificity |
Osteoclasts. {ECO:0000269|PubMed:10477767}.
|
| Top Pathways |
Calcium signaling pathway, Salivary secretion, Pancreatic secretion, Epstein-Barr virus infection, Oxytocin signaling pathway
|