Gene Symbol |
Amhr2
|
Entrez Gene |
29530
|
Alt Symbol |
-
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
anti-Mullerian hormone receptor, type II
|
Other Description |
AMH type II receptor|C14|MIS type II receptor|MISRII|MRII|anti-Muellerian hormone type II receptor|anti-Muellerian hormone type-2 receptor|anti-Mullerian hormone receptor type 11 SV1|anti-Mullerian hormone type 2 receptor
|
Swissprots |
Q62893 Q63045 Q9R0A7
|
Accessions |
EDL86839 EDL86840 Q62893 KJ923229 AIL92620 U42427 AAC52343 X71916 CAA50731 NM_030998 NP_112260
|
Function |
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
|
Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
Top Pathways |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway
|