Gene Symbol | SLPI |
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Entrez Gene | 6590 |
Alt Symbol | ALK1, ALP, BLPI, HUSI, HUSI-I, MPI, WAP4, WFDC4 |
Species | Human |
Gene Type | protein-coding |
Description | secretory leukocyte peptidase inhibitor |
Other Description | HUSI-1|WAP four-disulfide core domain protein 4|antileukoproteinase|mucus proteinase inhibitor|protease inhibitor WAP4|secretory leukocyte protease inhibitor (antileukoproteinase)|seminal proteinase inhibitor |
Swissprots | P03973 P07757 B2R5H8 |
Accessions | AAA60559 CAA28187 CAJ01313 CAN37611 CAY39338 EAW75869 P03973 AF114471 AAD19661 AK312192 BAG35125 AX772818 CAE06258 BC020708 AAH20708 DQ891365 ABM82291 DQ894545 ABM85471 X04470 CAA28158 X04503 CAA28188 NM_003064 NP_003055 |
Function | Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. May prevent elastase-mediated damage to oral and possibly other mucosal tissues. |
Subcellular Location | Secreted. |
Tissue Specificity | Mucous fluids. |
SLPI CRISPR/Cas9 KO Plasmid (h) - sc-418559 from Santa Cruz Biotechnology
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SLPI HDR Plasmid (h) - sc-418559-HDR from Santa Cruz Biotechnology
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SLPI Double Nickase Plasmid (h) - sc-418559-NIC from Santa Cruz Biotechnology
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SLPI Double Nickase Plasmid (h2) - sc-418559-NIC-2 from Santa Cruz Biotechnology
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SLPI CRISPR Activation Plasmid (h) - sc-418559-ACT from Santa Cruz Biotechnology
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SLPI CRISPR Activation Plasmid (h2) - sc-418559-ACT-2 from Santa Cruz Biotechnology
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SLPI Lentiviral Activation Particles (h) - sc-418559-LAC from Santa Cruz Biotechnology
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SLPI Lentiviral Activation Particles (h2) - sc-418559-LAC-2 from Santa Cruz Biotechnology
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SLPI siRNA (h) - sc-42977 from Santa Cruz Biotechnology
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SLPI shRNA Plasmid (h) - sc-42977-SH from Santa Cruz Biotechnology
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SLPI shRNA (h) Lentiviral Particles - sc-42977-V from Santa Cruz Biotechnology
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Mannose Phosphate Isomerase RNAi - H00004351-R01 from Novus Biologicals
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SLPI RNAi - H00006590-R01 from Novus Biologicals
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MISSION® esiRNA - EHU055351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19740 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19740 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00925 from Sigma-Aldrich
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SLPI siRNA (Human) - CRH4476 from Cohesion Biosciences
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SLPI - MBS8201584 from MyBioSource
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shRNA set against Human SLPI(NM_003064.2) - SHH222000 from Creative biogene
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SLPI shRNA Plasmid (Human) - CHH4476 from Cohesion Biosciences
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SLPI miRNA 3'UTR clone - MiUTR1H-09629 from Creative biogene
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