Gene Symbol | SYCP2 |
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Entrez Gene | 10388 |
Alt Symbol | SCP2 |
Species | Human |
Gene Type | protein-coding |
Description | synaptonemal complex protein 2 |
Other Description | SCP-2|hsSCP2|synaptonemal complex lateral element protein |
Swissprots | A2RUE5 Q9BX26 O75763 Q9NTX8 Q9UG27 Q5JX11 |
Accessions | EAW75426 EAW75427 Q9BX26 AK308889 AL080226 CAB45780 BC040566 AAH40566 BC132864 AAI32865 BC132870 AAI32871 BC146798 AAI46799 BQ575787 BX648091 BX649108 Y08982 CAA70171 XM_005260247 XP_005260304 XM_011528487 XP_011526789 XM_011528488 XP_011526790 XM_011528489 XP_011526791 XM_011528490 XP_011526792 XM_011528491 XP_011526793 XM_011528492 XP_011526794 XM_011528493 XP_011526795 XM_011528494 XP_011526796 XR_936494 NM_014258 NP_055073 |
Function | Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=In axial/lateral elements of the tripartite segments of synaptonemal complexes. {ECO:0000250}. |
SCP-2 CRISPR/Cas9 KO Plasmid (h) - sc-409780 from Santa Cruz Biotechnology
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SCP-2 HDR Plasmid (h) - sc-409780-HDR from Santa Cruz Biotechnology
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SCP-2 Double Nickase Plasmid (h) - sc-409780-NIC from Santa Cruz Biotechnology
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SCP-2 Double Nickase Plasmid (h2) - sc-409780-NIC-2 from Santa Cruz Biotechnology
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SCP-2 CRISPR Activation Plasmid (h) - sc-409780-ACT from Santa Cruz Biotechnology
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SCP-2 CRISPR Activation Plasmid (h2) - sc-409780-ACT-2 from Santa Cruz Biotechnology
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SCP-2 Lentiviral Activation Particles (h) - sc-409780-LAC from Santa Cruz Biotechnology
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SCP-2 Lentiviral Activation Particles (h2) - sc-409780-LAC-2 from Santa Cruz Biotechnology
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SCP-2 siRNA (h) - sc-37644 from Santa Cruz Biotechnology
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SCP-2 shRNA Plasmid (h) - sc-37644-SH from Santa Cruz Biotechnology
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SCP-2 shRNA (h) Lentiviral Particles - sc-37644-V from Santa Cruz Biotechnology
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SCP2 RNAi - H00010388-R01 from Novus Biologicals
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MISSION® esiRNA - EHU071141 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20878 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20878 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06299 from Sigma-Aldrich
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SYCP2 siRNA (Human) - CRH7037 from Cohesion Biosciences
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SYCP2 - MBS8221715 from MyBioSource
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shRNA set against Human SYCP2 (NM_014258.2) - SHH421512 from Creative biogene
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shRNA set against Human SYCP2(NM_014258.2) - SHR209946 from Creative biogene
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Human SYCP2 siRNA - orb267539 from Biorbyt
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SYCP2 shRNA Plasmid (Human) - CHH7037 from Cohesion Biosciences
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SYCP2 miRNA 3'UTR clone - MiUTR1H-10099 from Creative biogene
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