| Gene Symbol |
AGGF1
|
| Entrez Gene |
55109
|
| Alt Symbol |
GPATC7, GPATCH7, HSU84971, HUS84971, VG5Q
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
angiogenic factor with G patch and FHA domains 1
|
| Other Description |
G patch domain-containing protein 7|angiogenic factor VG5Q|vasculogenesis gene on 5q protein
|
| Swissprots |
Q53YS3 Q8N302 Q9NW66 Q9BU84 O00581
|
| Accessions |
AAR97617 EAW95787 EAW95788 EAW95789 Q8N302 AI453097 AK001145 BAA91519 AK097255 AK289394 BAF82083 AW500409 AW958325 AY500994 AAR97615 BC002828 AAH02828 BC015478 AAH15478 BC029382 AAH29382 BC032844 AAH32844 BC073864 BE077189 BI561566 BM998072 BX648120 CF994178 DR157679 JF432544 ADZ15761 U84971 AAB60856 NM_018046 NP_060516
|
| Function |
Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion. {ECO:0000269|PubMed:14961121}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:14961121}. Secreted {ECO:0000269|PubMed:14961121}. Note=Cytoplasmic in microvascular endothelial cells. Upon angiogenesis, when endothelial cell tube formation is initiated, it is secreted.
|
| Tissue Specificity |
Widely expressed. Expressed in endothelial cells, vascular smooth muscle cells and osteoblasts. Expressed in umbilical vein endothelial cells and microvascular endothelial cells. {ECO:0000269|PubMed:14961121}.
|