Gene Symbol | KCNH3 |
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Entrez Gene | 23416 |
Alt Symbol | BEC1, ELK2, Kv12.2 |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, voltage gated eag related subfamily H, member 3 |
Other Description | ELK channel 2|brain-specific eag-like channel 1|ether-a-go-go K(+) channel family member|ether-a-go-go-like potassium channel 2|potassium voltage-gated channel subfamily H member 3|potassium voltage-gated channel, subfamily H (eag-related), member 3|voltage-gated potassium channel subunit Kv12.2 |
Swissprots | Q9ULD8 Q9UQ06 |
Accessions | EAW58073 EAW58074 Q9ULD8 AB022696 BAA83590 AB033108 BAA86596 BC033141 AAH33141 BC144254 BC150602 AAI50603 XM_005268752 XP_005268809 XM_006719313 XP_006719376 XM_011538085 XP_011536387 XM_011538086 XP_011536388 XM_011538087 XP_011536389 XM_011538088 XP_011536390 NM_012284 NP_036416 |
Function | Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current with fast inactivation. Channel properties may be modulated by cAMP and subunit assembly. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Detected only in brain, in particular in the telencephalon. Detected in the cerebral cortex, occipital pole, frontal and temporal lobe, putamen, amygdala, hippocampus and caudate nucleus. |
KCNH3 CRISPR/Cas9 KO Plasmid (h) - sc-411737 from Santa Cruz Biotechnology
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KCNH3 HDR Plasmid (h) - sc-411737-HDR from Santa Cruz Biotechnology
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KCNH3 Double Nickase Plasmid (h) - sc-411737-NIC from Santa Cruz Biotechnology
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KCNH3 Double Nickase Plasmid (h2) - sc-411737-NIC-2 from Santa Cruz Biotechnology
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KCNH3 CRISPR Activation Plasmid (h) - sc-411737-ACT from Santa Cruz Biotechnology
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KCNH3 CRISPR Activation Plasmid (h2) - sc-411737-ACT-2 from Santa Cruz Biotechnology
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KCNH3 Lentiviral Activation Particles (h) - sc-411737-LAC from Santa Cruz Biotechnology
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KCNH3 Lentiviral Activation Particles (h2) - sc-411737-LAC-2 from Santa Cruz Biotechnology
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KCNH3 siRNA (h) - sc-95657 from Santa Cruz Biotechnology
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KCNH3 shRNA Plasmid (h) - sc-95657-SH from Santa Cruz Biotechnology
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KCNH3 shRNA (h) Lentiviral Particles - sc-95657-V from Santa Cruz Biotechnology
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Kv12.2 RNAi - H00023416-R03 from Novus Biologicals
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MISSION® esiRNA - EHU010751 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10943 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10943 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02523 from Sigma-Aldrich
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KCNH3 siRNA (Human) - CRH8255 from Cohesion Biosciences
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KCNH3, siRNA - MBS8227898 from MyBioSource
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shRNA set against Human KCNH3 (NM_012284.1) - SHH323059 from Creative biogene
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shRNA set against Human KCNH3(NM_012284.1) - SHL182440 from Creative biogene
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Human KCNH3 siRNA - orb268757 from Biorbyt
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KCNH3 shRNA Plasmid (Human) - CHH8255 from Cohesion Biosciences
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KCNH3 miRNA 3'UTR clone - MiUTR1H-05109 from Creative biogene
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