Gene Symbol | BBS10 |
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Entrez Gene | 79738 |
Alt Symbol | C12orf58 |
Species | Human |
Gene Type | protein-coding |
Description | Bardet-Biedl syndrome 10 |
Other Description | Bardet-Biedl syndrome 10 protein |
Swissprots | Q9H5D2 Q8TAM1 Q96CW2 |
Accessions | CAX86889 CAX86890 CDI06881 EAW97322 EAW97323 Q8TAM1 AI673014 AK027213 BAB15695 AK225585 AK304178 BAH14128 BC013795 AAH13795 BC026355 AAH26355 DA095453 DR155669 JF432744 ADZ15961 NM_024685 NP_078961 |
Function | Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation. {ECO:0000269|PubMed:19190184, ECO:0000269|PubMed:20080638}. |
Subcellular Location | Cell projection, cilium {ECO:0000269|PubMed:19190184}. Note=Located within the basal body of the primary cilium of differentiating preadipocytes. |
BBS10 CRISPR/Cas9 KO Plasmid (h) - sc-408538 from Santa Cruz Biotechnology
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BBS10 HDR Plasmid (h) - sc-408538-HDR from Santa Cruz Biotechnology
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BBS10 Double Nickase Plasmid (h) - sc-408538-NIC from Santa Cruz Biotechnology
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BBS10 Double Nickase Plasmid (h2) - sc-408538-NIC-2 from Santa Cruz Biotechnology
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BBS10 CRISPR Activation Plasmid (h) - sc-408538-ACT from Santa Cruz Biotechnology
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BBS10 CRISPR Activation Plasmid (h2) - sc-408538-ACT-2 from Santa Cruz Biotechnology
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BBS10 Lentiviral Activation Particles (h) - sc-408538-LAC from Santa Cruz Biotechnology
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BBS10 Lentiviral Activation Particles (h2) - sc-408538-LAC-2 from Santa Cruz Biotechnology
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BBS10 siRNA (h) - sc-72620 from Santa Cruz Biotechnology
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BBS10 shRNA Plasmid (h) - sc-72620-SH from Santa Cruz Biotechnology
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BBS10 shRNA (h) Lentiviral Particles - sc-72620-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU043231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3878 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3878 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09318 from Sigma-Aldrich
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BBS10 siRNA (Human) - CRJ2527 from Cohesion Biosciences
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BBS10 - MBS8211622 from MyBioSource
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shRNA set against Human BBS10 (NM_024685.3) - SHH245118 from Creative biogene
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Human BBS10 siRNA - orb273028 from Biorbyt
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BBS10 shRNA Plasmid (Human) - CHJ2527 from Cohesion Biosciences
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BBS10 miRNA 3'UTR clone - MiUTR1H-00823 from Creative biogene
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