Gene Symbol | IFNA8 |
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Entrez Gene | 3445 |
Alt Symbol | IFN-alphaB |
Species | Human |
Gene Type | protein-coding |
Description | interferon, alpha 8 |
Other Description | IFN-alpha-8|interferon alpha type 201|interferon alpha-8|interferon alpha-B|interferon alpha-B'|interferon alpha-B2|leIF B |
Swissprots | P32881 P01565 Q5VWV7 P09236 Q5VYQ3 |
Accessions | CAA26903 EAW58610 P32881 BC104828 AAI04829 BC104830 AAI04831 K01900 AAA52716 V00545 CAA23806 V00550 CAA23811 NM_002170 NP_002161 |
Function | Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. |
Subcellular Location | Secreted. |
Top Pathways | Cytosolic DNA-sensing pathway, Tuberculosis, Herpes simplex infection, Influenza A, PI3K-Akt signaling pathway |
IFN-α8 CRISPR/Cas9 KO Plasmid (h) - sc-410832 from Santa Cruz Biotechnology
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IFN-α8 HDR Plasmid (h) - sc-410832-HDR from Santa Cruz Biotechnology
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IFN-α8 Double Nickase Plasmid (h) - sc-410832-NIC from Santa Cruz Biotechnology
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IFN-α8 Double Nickase Plasmid (h2) - sc-410832-NIC-2 from Santa Cruz Biotechnology
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IFN-α8 CRISPR Activation Plasmid (h) - sc-410832-ACT from Santa Cruz Biotechnology
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IFN-α8 CRISPR Activation Plasmid (h2) - sc-410832-ACT-2 from Santa Cruz Biotechnology
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IFN-α8 Lentiviral Activation Particles (h) - sc-410832-LAC from Santa Cruz Biotechnology
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IFN-α8 Lentiviral Activation Particles (h2) - sc-410832-LAC-2 from Santa Cruz Biotechnology
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IFN-α8 siRNA (h) - sc-92474 from Santa Cruz Biotechnology
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IFN-α8 shRNA Plasmid (h) - sc-92474-SH from Santa Cruz Biotechnology
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IFN-α8 shRNA (h) Lentiviral Particles - sc-92474-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10489 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10489 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04186 from Sigma-Aldrich
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IFNA8 siRNA (Human) - CRH2334 from Cohesion Biosciences
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IFN-alpha B2/IFN-alpha 8 RNAi - H00003445-R01 from Novus Biologicals
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IFNA8 - MBS8228995 from MyBioSource
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shRNA set against Human IFNA8 (NM_002170.3) - SHH317105 from Creative biogene
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Human IFNA8 siRNA - orb262836 from Biorbyt
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IFNA8 shRNA Plasmid (Human) - CHH2334 from Cohesion Biosciences
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IFNA8 miRNA 3'UTR clone - MiUTR1H-04812 from Creative biogene
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