Gene Symbol |
LGALS7B
|
Entrez Gene |
653499
|
Alt Symbol |
GAL7, Gal-7, HKL-14, LGALS7, PI7
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
lectin, galactoside-binding, soluble, 7B
|
Other Description |
galectin 7B|galectin-7|galectin-7B|keratinocyte lectin 14|lectin galactoside-binding soluble 7|p53-induced gene 1 protein|p53-induced protein 1
|
Swissprots |
Q6IB87 P47929
|
Accessions |
CAD48636 EAW56818 P47929 AW015224 BC042911 AAH42911 BC061588 AAH61588 BC073743 AAH73743 L07769 AAA67899 U06643 AAA86820 NM_001042507 NP_001035972
|
Function |
Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. {ECO:0000269|PubMed:11706006}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:11706006}. Nucleus {ECO:0000269|PubMed:11706006}. Secreted {ECO:0000305}. Note=May be secreted by a non-classical secretory pathway.
|
Tissue Specificity |
Mainly expressed in stratified squamous epithelium.
|