IL5RA
| Gene Symbol | IL5RA |
|---|---|
| Entrez Gene | 3568 |
| Alt Symbol | CD125, CDw125, HSIL5R3, IL5R |
| Species | Human |
| Gene Type | protein-coding |
| Description | interleukin 5 receptor, alpha |
| Other Description | CD125 antigen|IL-5 receptor subunit alpha|IL-5R subunit alpha|interleukin 5 receptor type 3|interleukin-5 receptor alpha chain|interleukin-5 receptor subunit alpha |
| Swissprots | Q01344 B4E2G0 Q14633 Q6ISX9 B3IU77 Q15469 |
| Accessions | AAT45457 CAA01731 CAA01793 CAA01794 EAW63879 EAW63880 EAW63881 EAW63882 EAW63883 EAW63884 Q01344 AB288089 BAG49561 AB288090 BAG49562 AK304256 BAG65122 BC027599 AAH27599 BI520196 BX118481 DB222974 DB229011 M75914 AAA36110 M96651 AAA59151 M96652 AAA59152 X61176 CAA43483 X61178 CAA43485 X62156 CAA44081 XM_011533677 XP_011531979 XM_011533678 XP_011531980 XM_011533679 XP_011531981 NM_000564 NP_000555 NM_001243099 NP_001230028 NM_175724 NP_783851 NM_175725 NP_783852 NM_175726 NP_783853 NM_175727 NP_783854 NM_175728 NP_783855 |
| Function | This is the receptor for interleukin-5. The alpha chain binds to IL5. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed on eosinophils and basophils. |
| Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage |
IL-5Rα CRISPR/Cas9 KO Plasmid (h) - sc-408743 from Santa Cruz Biotechnology
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IL-5Rα HDR Plasmid (h) - sc-408743-HDR from Santa Cruz Biotechnology
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IL-5Rα Double Nickase Plasmid (h) - sc-408743-NIC from Santa Cruz Biotechnology
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IL-5Rα Double Nickase Plasmid (h2) - sc-408743-NIC-2 from Santa Cruz Biotechnology
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IL-5Rα CRISPR Activation Plasmid (h) - sc-408743-ACT from Santa Cruz Biotechnology
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IL-5Rα CRISPR Activation Plasmid (h2) - sc-408743-ACT-2 from Santa Cruz Biotechnology
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IL-5Rα Lentiviral Activation Particles (h) - sc-408743-LAC from Santa Cruz Biotechnology
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IL-5Rα Lentiviral Activation Particles (h2) - sc-408743-LAC-2 from Santa Cruz Biotechnology
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IL-5Rα siRNA (h) - sc-29369 from Santa Cruz Biotechnology
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IL-5Rα shRNA Plasmid (h) - sc-29369-SH from Santa Cruz Biotechnology
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IL-5Rα shRNA (h) Lentiviral Particles - sc-29369-V from Santa Cruz Biotechnology
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IL-5 R alpha/CD125 RNAi - H00003568-R09 from Novus Biologicals
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IL-5 R alpha/CD125 RNAi - H00003568-R07 from Novus Biologicals
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IL-5 R alpha/CD125 RNAi - H00003568-R12 from Novus Biologicals
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IL-5 R alpha/CD125 RNAi - H00003568-R11 from Novus Biologicals
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MISSION® esiRNA - EHU083161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10636 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10636 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05369 from Sigma-Aldrich
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IL5RA siRNA (Human) - CRH2385 from Cohesion Biosciences
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IL-5 R alpha/CD125 RNAi - H00003568-R10 from Novus Biologicals
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IL-5 R alpha/CD125 RNAi - H00003568-R08 from Novus Biologicals
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IL5RA - MBS8209882 from MyBioSource
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shRNA set against Human IL5RA (NM_000564.4) - SHH319033 from Creative biogene
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Human IL5RA siRNA - orb262887 from Biorbyt
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