Gene Symbol | RGS12 |
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Entrez Gene | 6002 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | regulator of G-protein signaling 12 |
Other Description | regulator of G-protein signalling 12 |
Swissprots | B7Z764 Q147X0 O14922 B1AQ32 B1AQ31 O75338 E7EMN9 O14923 O43510 Q8WX95 O14924 B1AQ30 |
Accessions | AAB96644 AAB96645 AAB96646 EAW82465 EAW82466 EAW82467 EAW82468 EAW82469 EAW82470 EAW82471 EAW82472 O14924 AF030109 AAB84186 AF030110 AAB84007 AF030111 AAB84114 AF030112 AAB84187 AF035152 AAC39835 AF464735 AAL69959 AF464736 AAL69960 AF464737 AAL69961 AI870015 AK123325 BAG53889 AK290805 BAF83494 AK293767 BAH11592 AK301510 BAH13500 AK303135 BAH13904 AK308734 AK310999 AY987042 AAY26403 BC012118 BC028154 AAH28154 BC106944 AAI06945 BC118594 AAI18595 BC167850 AAI67850 BE048490 BI861043 BM718427 BM984992 CB242608 CB529269 DQ575785 XM_006713905 XP_006713968 XM_006713906 XP_006713969 XM_006713907 XP_006713970 XM_011513542 XP_011511844 XM_011513543 XP_011511845 XR_427479 XR_924987 NM_002926 NP_002917 NM_198227 NP_937870 NM_198229 NP_937872 NM_198230 NM_198430 NM_198432 NM_198587 |
Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:10869340}. |
Tissue Specificity | Isoform 3 is brain specific. |
RGS12 CRISPR/Cas9 KO Plasmid (h) - sc-409676 from Santa Cruz Biotechnology
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RGS12 HDR Plasmid (h) - sc-409676-HDR from Santa Cruz Biotechnology
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RGS12 Double Nickase Plasmid (h) - sc-409676-NIC from Santa Cruz Biotechnology
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RGS12 Double Nickase Plasmid (h2) - sc-409676-NIC-2 from Santa Cruz Biotechnology
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RGS12 CRISPR Activation Plasmid (h) - sc-409676-ACT from Santa Cruz Biotechnology
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RGS12 CRISPR Activation Plasmid (h2) - sc-409676-ACT-2 from Santa Cruz Biotechnology
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RGS12 Lentiviral Activation Particles (h) - sc-409676-LAC from Santa Cruz Biotechnology
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RGS12 Lentiviral Activation Particles (h2) - sc-409676-LAC-2 from Santa Cruz Biotechnology
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RGS12 siRNA (h) - sc-40671 from Santa Cruz Biotechnology
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RGS12 shRNA Plasmid (h) - sc-40671-SH from Santa Cruz Biotechnology
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RGS12 shRNA (h) Lentiviral Particles - sc-40671-V from Santa Cruz Biotechnology
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RGS12 RNAi - H00006002-R01 from Novus Biologicals
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RGS12 RNAi - H00006002-R03 from Novus Biologicals
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MISSION® esiRNA - EHU093251 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18217 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18217 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09073 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01277 from Sigma-Aldrich
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RGS12 siRNA (Human) - CRH4070 from Cohesion Biosciences
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RGS12 RNAi - H00006002-R02 from Novus Biologicals
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RGS12 - MBS8232709 from MyBioSource
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shRNA set against Human RGS12(NM_002926.3) - SHR178836 from Creative biogene
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shRNA set against Human RGS12(NM_198227.1) - SHR178854 from Creative biogene
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shRNA set against Human RGS12(NM_198229.2) - SHR178926 from Creative biogene
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Human RGS12 siRNA - orb264572 from Biorbyt
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