Gene Symbol | PRDX5 |
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Entrez Gene | 25824 |
Alt Symbol | ACR1, AOEB166, B166, HEL-S-55, PLP, PMP20, PRDX6, PRXV, SBBI10, prx-V |
Species | Human |
Gene Type | protein-coding |
Description | peroxiredoxin 5 |
Other Description | Alu co-repressor 1|TPx type VI|antioxidant enzyme B166|epididymis secretory protein Li 55|liver tissue 2D-page spot 71B|peroxiredoxin V|peroxiredoxin-5, mitochondrial|peroxisomal antioxidant enzyme|thioredoxin peroxidase PMP20|thioredoxin reductase |
Swissprots | Q9UKX4 A6NG06 P30044 A6NC19 Q6IAF2 Q9UBU5 Q9UJU4 B7ZLJ4 Q14CK0 B7ZVW3 |
Accessions | ABB05181 CAJ42730 CBX32673 P30044 AA187737 AF110731 AAF03750 AF112212 AAF17200 AF124993 AAF27531 AF197952 AAF04856 AF231705 AAF78899 AF242525 AAF99605 AJ249483 CAB62210 BC110983 AAI10984 BC113723 AAI13724 BC113725 AAI13726 BC143849 AAI43850 BC171733 AAI71733 BU598032 CR457203 CAG33484 FJ224298 ACI45990 HQ258129 ADR82883 XM_005273882 XP_005273939 NM_012094 NP_036226 NM_181651 NP_857634 NM_181652 NP_857635 |
Function | Reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin system. Involved in intracellular redox signaling. |
Subcellular Location | Isoform Mitochondrial: Mitochondrion. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:10521424}. |
Top Pathways | Peroxisome |
PRX V CRISPR/Cas9 KO Plasmid (h) - sc-402681 from Santa Cruz Biotechnology
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PRX V HDR Plasmid (h) - sc-402681-HDR from Santa Cruz Biotechnology
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PRX V Double Nickase Plasmid (h) - sc-402681-NIC from Santa Cruz Biotechnology
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PRX V Double Nickase Plasmid (h2) - sc-402681-NIC-2 from Santa Cruz Biotechnology
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PRX V CRISPR Activation Plasmid (h) - sc-402681-ACT from Santa Cruz Biotechnology
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PRX V CRISPR Activation Plasmid (h2) - sc-402681-ACT-2 from Santa Cruz Biotechnology
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PRX V Lentiviral Activation Particles (h) - sc-402681-LAC from Santa Cruz Biotechnology
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PRX V Lentiviral Activation Particles (h2) - sc-402681-LAC-2 from Santa Cruz Biotechnology
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PRX V siRNA (h) - sc-40837 from Santa Cruz Biotechnology
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PRX V shRNA Plasmid (h) - sc-40837-SH from Santa Cruz Biotechnology
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PRX V shRNA (h) Lentiviral Particles - sc-40837-V from Santa Cruz Biotechnology
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Peroxiredoxin 5 RNAi - H00025824-R03 from Novus Biologicals
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Peroxiredoxin 5 RNAi - H00025824-R01 from Novus Biologicals
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Peroxiredoxin 6 RNAi - H00009588-R01 from Novus Biologicals
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MISSION® esiRNA - EHU062211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17386 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17386 from Sigma-Aldrich
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PRDX5 siRNA (Human) - CRH8523 from Cohesion Biosciences
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Peroxiredoxin 5 RNAi - H00025824-R02 from Novus Biologicals
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shRNA set against Human PRDX5 (NM_181652.2) - SHH382348 from Creative biogene
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PRDX5 shRNA Plasmid (Human) - CHH8523 from Cohesion Biosciences
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PRDX5 miRNA 3'UTR clone - MiUTR3H-08581 from Creative biogene
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PRDX5 miRNA 3'UTR clone - MiUTR3H-08582 from Creative biogene
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PRDX5 miRNA 3'UTR clone - MiUTR3H-08583 from Creative biogene
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