Gene Symbol | SPINK2 |
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Entrez Gene | 6691 |
Alt Symbol | HUSI-II |
Species | Human |
Gene Type | protein-coding |
Description | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
Other Description | epididymis tissue protein Li 172|serine protease inhibitor Kazal-type 2 |
Swissprots | P20155 Q6FGH2 |
Accessions | AAB59431 CAS01774 EAX05512 EAX05513 EAX05514 EAX05515 P20155 AA776754 AA973772 AK312222 BAG35155 AV743457 AW592089 BC022514 AAH22514 BF589674 BI520020 BI561149 BI562269 BU853655 CR542135 CAG46932 DB451710 DQ596286 DQ895533 ABM86459 EU176199 ABW03650 GU727622 ADU87624 HY020998 HY028205 HY043430 HY055610 X57655 CAB37834 XM_011534405 XP_011532707 XM_011534406 XP_011532708 NM_001271718 NP_001258647 NM_001271719 NP_001258648 NM_001271720 NP_001258649 NM_001271721 NP_001258650 NM_001271722 NP_001258651 NM_021114 NP_066937 NR_073417 NR_073418 NR_073419 |
Function | Strong inhibitor of acrosin in male and/or female genital tract. Also inhibits trypsin. {ECO:0000269|PubMed:19422058}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in epididymis (at protein level). {ECO:0000269|PubMed:20736409}. |
SPINK2 CRISPR/Cas9 KO Plasmid (h) - sc-411017 from Santa Cruz Biotechnology
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SPINK2 HDR Plasmid (h) - sc-411017-HDR from Santa Cruz Biotechnology
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SPINK2 Double Nickase Plasmid (h) - sc-411017-NIC from Santa Cruz Biotechnology
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SPINK2 Double Nickase Plasmid (h2) - sc-411017-NIC-2 from Santa Cruz Biotechnology
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SPINK2 CRISPR Activation Plasmid (h) - sc-411017-ACT from Santa Cruz Biotechnology
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SPINK2 CRISPR Activation Plasmid (h2) - sc-411017-ACT-2 from Santa Cruz Biotechnology
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SPINK2 Lentiviral Activation Particles (h) - sc-411017-LAC from Santa Cruz Biotechnology
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SPINK2 Lentiviral Activation Particles (h2) - sc-411017-LAC-2 from Santa Cruz Biotechnology
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SPINK2 siRNA (h) - sc-88884 from Santa Cruz Biotechnology
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SPINK2 shRNA Plasmid (h) - sc-88884-SH from Santa Cruz Biotechnology
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SPINK2 shRNA (h) Lentiviral Particles - sc-88884-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU027201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20481 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20481 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02380 from Sigma-Aldrich
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SPINK2 siRNA (Human) - CRH4561 from Cohesion Biosciences
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SPINK2 - MBS8219735 from MyBioSource
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shRNA set against Human SPINK2 (NM_021114.2) - SHH416768 from Creative biogene
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shRNA set against Human SPINK2(NM_021114.2) - SHL029008 from Creative biogene
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Human SPINK2 siRNA - orb265063 from Biorbyt
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SPINK2 shRNA Plasmid (Human) - CHH4561 from Cohesion Biosciences
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SPINK2 miRNA 3'UTR clone - MiUTR1H-09843 from Creative biogene
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