Gene Symbol |
Ak6
|
Entrez Gene |
102238592
|
Alt Symbol |
AK/ATPase
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
adenylate kinase 6
|
Other Description |
AK/ATPase {ECO:0000255|HAMAP-Rule:MF_03173}|AK6 {ECO:0000255|HAMAP-Rule:MF_03173}|ATP-AMP transphosphorylase 6|adenylate kinase isoenzyme 6|adenylate kinase isoenzyme 6 {ECO:0000255|HAMAP-Rule:MF_03173}|coilin-interacting nuclear ATPase protein {ECO:0000255|HAMAP-Rule:MF_03173}|dual activity adenylate kinase/ATPase {ECO:0000255|HAMAP-Rule:MF_03173}
|
Swissprots |
Q5EB68 A6XB81
|
Accessions |
EDM10206 Q5EB68 BC089989 AAH89989 BQ205289 DQ323055 ABC50104 FQ214172 NM_001012463 NP_001012481
|
Function |
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation. {ECO:0000255|HAMAP-Rule:MF_03173}.
|
Subcellular Location |
Nucleus, nucleoplasm {ECO:0000255|HAMAP- Rule:MF_03173}. Nucleus, Cajal body {ECO:0000255|HAMAP- Rule:MF_03173}. Note=Displays widespread diffuse nucleoplasmic distribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells. {ECO:0000255|HAMAP-Rule:MF_03173}.
|
Top Pathways |
Ribosome biogenesis in eukaryotes, Purine metabolism
|