| Gene Symbol |
Egf
|
| Entrez Gene |
25313
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
epidermal growth factor
|
| Other Description |
pro-epidermal growth factor
|
| Swissprots |
Q63183 P07522
|
| Accessions |
EDL82179 EDL82180 P07522 BC062030 AAH62030 JX149564 JX437943 AFR51946 U04842 AAB60436 NM_012842 NP_036974
|
| Function |
EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Top Pathways |
Endocytosis, Rap1 signaling pathway, Hepatitis C, PI3K-Akt signaling pathway, Choline metabolism in cancer
|