Gene Symbol | NDUFB2 |
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Entrez Gene | 4708 |
Alt Symbol | AGGG, CI-AGGG |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa |
Other Description | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial|NADH-ubiquinone oxidoreductase AGGG subunit|complex I AGGG subunit|complex I-AGGG |
Swissprots | Q6FGI6 O95178 |
Accessions | AAD43191 EAL24024 EAW83958 EAW83959 EAW83960 EAW83961 EAW83962 O95178 AF050639 AAD05428 AF067166 AAD32450 BC001168 BC063026 AAH63026 CR542121 CAG46918 NM_004546 NP_004537 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFB2 CRISPR/Cas9 KO Plasmid (h) - sc-410900 from Santa Cruz Biotechnology
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NDUFB2 HDR Plasmid (h) - sc-410900-HDR from Santa Cruz Biotechnology
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NDUFB2 Double Nickase Plasmid (h) - sc-410900-NIC from Santa Cruz Biotechnology
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NDUFB2 Double Nickase Plasmid (h2) - sc-410900-NIC-2 from Santa Cruz Biotechnology
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NDUFB2 CRISPR Activation Plasmid (h) - sc-410900-ACT from Santa Cruz Biotechnology
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NDUFB2 CRISPR Activation Plasmid (h2) - sc-410900-ACT-2 from Santa Cruz Biotechnology
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NDUFB2 Lentiviral Activation Particles (h) - sc-410900-LAC from Santa Cruz Biotechnology
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NDUFB2 Lentiviral Activation Particles (h2) - sc-410900-LAC-2 from Santa Cruz Biotechnology
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NDUFB2 siRNA (h) - sc-89375 from Santa Cruz Biotechnology
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NDUFB2 shRNA Plasmid (h) - sc-89375-SH from Santa Cruz Biotechnology
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NDUFB2 shRNA (h) Lentiviral Particles - sc-89375-V from Santa Cruz Biotechnology
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NDUFB2 RNAi - H00004708-R01 from Novus Biologicals
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MISSION® esiRNA - EHU066921 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15156 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15156 from Sigma-Aldrich
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NDUFB2 siRNA (Human) - CRH3122 from Cohesion Biosciences
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shRNA set against Human NDUFB2 (NM_004546.2) - SHH350720 from Creative biogene
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shRNA set against Human NDUFB2(NM_004546.2) - SHR005160 from Creative biogene
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Human NDUFB2 siRNA - orb263624 from Biorbyt
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NDUFB2 shRNA Plasmid (Human) - CHH3122 from Cohesion Biosciences
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NDUFB2 miRNA 3'UTR clone - MiUTR1H-06703 from Creative biogene
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