Gene Symbol | PGGT1B |
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Entrez Gene | 5229 |
Alt Symbol | BGGI, GGTI |
Species | Human |
Gene Type | protein-coding |
Description | protein geranylgeranyltransferase type I, beta subunit |
Other Description | CTC-428G20.3|GGTase-I-beta|geranylgeranyl transferase type I subunit beta|geranylgeranyl transferase type-1 subunit beta|geranylgeranyltransferase type I beta subunit|type I protein geranyl-geranyltransferase subunit beta |
Swissprots | Q5MJP9 P53609 |
Accessions | EAW48968 EAW48969 P53609 AK096154 AL520655 AW382606 AY780790 AAV98360 BC111924 AAI11925 BC118496 AAI18497 DA024020 HG498356 XM_005272020 XP_005272077 XM_005272022 XP_005272079 XM_011543490 XP_011541792 XM_011543491 XP_011541793 XM_011543492 XP_011541794 NM_005023 NP_005014 |
Function | Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Known substrates include RAC1, RAC2, RAP1A and RAP1B. {ECO:0000269|PubMed:8106351}. |
GGTase-Iβ siRNA (h) - sc-40882 from Santa Cruz Biotechnology
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GGTase-Iβ shRNA Plasmid (h) - sc-40882-SH from Santa Cruz Biotechnology
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GGTase-Iβ shRNA (h) Lentiviral Particles - sc-40882-V from Santa Cruz Biotechnology
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PGGT1B RNAi - H00005229-R01 from Novus Biologicals
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MISSION® esiRNA - EHU112171 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16684 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16684 from Sigma-Aldrich
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PGGT1B siRNA (Human) - CRH3494 from Cohesion Biosciences
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shRNA set against Human PGGT1B (NM_005023.3) - SHH374236 from Creative biogene
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shRNA set against Human PGGT1B(NM_005023.3) - SHR109038 from Creative biogene
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Human PGGT1B siRNA - orb263996 from Biorbyt
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PGGT1B shRNA Plasmid (Human) - CHH3494 from Cohesion Biosciences
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PGGT1B miRNA 3'UTR clone - MiUTR1H-07821 from Creative biogene
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