Gene Symbol | KLF13 |
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Entrez Gene | 51621 |
Alt Symbol | BTEB3, FKLF2, NSLP1, RFLAT-1, RFLAT1 |
Species | Human |
Gene Type | protein-coding |
Description | Kruppel-like factor 13 |
Other Description | BTE-binding protein 3|Krueppel-like factor 13|RANTES factor of late activated T lymphocytes-1|basic transcription element binding protein 3|novel Sp1-like zinc finger transcription factor 1|transcription factor BTEB3|transcription factor NSLP1 |
Swissprots | Q9Y356 Q9Y2Y9 |
Accessions | EAW61265 Q9Y2Y9 AF132599 AAD26864 AF150628 AAD34020 AI074707 AI084187 AK093758 AK127052 AL390127 BC010438 AAH10438 BC012741 AAH12741 BC012782 BC013946 AAH13946 BC035503 BC064552 BF797908 BM477172 BX096457 BX474032 KJ534876 AHW56516 KJ535015 AHW56654 NR_033741 NM_001302461 NP_001289390 NM_015995 NP_057079 |
Function | Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells. {ECO:0000269|PubMed:11477107}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Ubiquitous. |
RFLAT-1 CRISPR/Cas9 KO Plasmid (h) - sc-404618 from Santa Cruz Biotechnology
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RFLAT-1 HDR Plasmid (h) - sc-404618-HDR from Santa Cruz Biotechnology
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RFLAT-1 Double Nickase Plasmid (h) - sc-404618-NIC from Santa Cruz Biotechnology
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RFLAT-1 Double Nickase Plasmid (h2) - sc-404618-NIC-2 from Santa Cruz Biotechnology
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RFLAT-1 CRISPR Activation Plasmid (h) - sc-404618-ACT from Santa Cruz Biotechnology
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RFLAT-1 CRISPR Activation Plasmid (h2) - sc-404618-ACT-2 from Santa Cruz Biotechnology
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RFLAT-1 Lentiviral Activation Particles (h) - sc-404618-LAC from Santa Cruz Biotechnology
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RFLAT-1 Lentiviral Activation Particles (h2) - sc-404618-LAC-2 from Santa Cruz Biotechnology
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RFLAT-1 siRNA (h) - sc-38234 from Santa Cruz Biotechnology
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RFLAT-1 shRNA Plasmid (h) - sc-38234-SH from Santa Cruz Biotechnology
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RFLAT-1 shRNA (h) Lentiviral Particles - sc-38234-V from Santa Cruz Biotechnology
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KLF13 RNAi - H00051621-R01 from Novus Biologicals
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MISSION® esiRNA - EHU097931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11247 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11247 from Sigma-Aldrich
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KLF13 siRNA (Human) - CRH9864 from Cohesion Biosciences
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shRNA set against Human KLF13(NM_015995.2) - SHL199782 from Creative biogene
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KLF13 shRNA Plasmid (Human) - CHH9864 from Cohesion Biosciences
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KLF13 miRNA 3'UTR clone - MiUTR1H-05356 from Creative biogene
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