| Gene Symbol |
TMEM106B
|
| Entrez Gene |
54664
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane protein 106B
|
| Other Description |
-
|
| Swissprots |
Q53FL9 A4D108 Q8N4L0 Q9NUM4
|
| Accessions |
AAQ96840 CAC51183 EAL24296 EAW93638 EAW93639 EAW93640 EAW93641 EAW93642 Q9NUM4 AK001834 AK002135 BAA92099 AK090805 AK223263 BAD96983 AK311651 BC028108 AAH28108 BC033901 AAH33901 BC039741 AAH39741 DA452299 HQ447341 ADQ31827 XM_005249789 XP_005249846 NM_001134232 NP_001127704 NM_018374 NP_060844
|
| Function |
Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lysosomes along dendrites. Required for dendrite branching. {ECO:0000269|PubMed:23136129, ECO:0000269|PubMed:24357581}.
|
| Subcellular Location |
Late endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein.
|
| Tissue Specificity |
Expressed in frontal cortex.
|