Gene Symbol |
Pla2g10
|
Entrez Gene |
26565
|
Alt Symbol |
PLA2GX, mGXsPLA2, sPLA2-X
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
phospholipase A2, group X
|
Other Description |
GX sPLA2|group 10 secretory phospholipase A2|group X secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 10
|
Swissprots |
Q9EQK6 Q9QXX3
|
Accessions |
EDK97369 EDK97370 Q9QXX3 AF166097 AAF04498 AF210429 AAG43522 AK076921 BAC36530 AV075661 BC028879 AAH28879 CJ047253 KC789644 AGO86070 NM_001291009 NP_001277938 NM_011987 NP_036117 NR_110990
|
Function |
PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Has a powerful potency for releasing arachidonic acid from cell membrane phospholipids.
|
Subcellular Location |
Secreted.
|
Tissue Specificity |
Expressed in various tissues including the lung, thymus, and spleen.
|
Top Pathways |
Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism
|