| Gene Symbol |
PPP6R2
|
| Entrez Gene |
9701
|
| Alt Symbol |
KIAA0685, PP6R2, SAP190, SAPS2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protein phosphatase 6, regulatory subunit 2
|
| Other Description |
SAPS domain family, member 2|serine/threonine-protein phosphatase 6 regulatory subunit 2
|
| Swissprots |
B7Z7T3 Q7Z2L2 Q7Z5G5 Q9UGB9 A6PVG3 Q7Z731 O75170 Q5U5P3
|
| Accessions |
EAW73530 EAW73531 EAW73532 EAW73533 EAW73534 O75170 AA743798 AB014585 BAA31660 AK002063 BAG51009 AK022669 BAG51102 AK024148 AK097210 AK302472 BAH13719 BC000976 AAH00976 BC006568 AAH06568 BC022346 BC032664 AAH32664 BC041698 AAH41698 BC052995 AAH52995 DB452735 XM_005261960 XP_005262017 XM_006724431 XP_006724494 XM_006724434 XP_006724497 XM_006724435 XP_006724498 XM_011530720 XP_011529022 XM_011530721 XP_011529023 XM_011530722 XP_011529024 XM_011530723 XP_011529025 XM_011530724 XP_011529026 XM_011530725 XP_011529027 XM_011530726 XP_011529028 XM_011530727 XP_011529029 XM_011530728 XP_011529030 XM_011530729 XP_011529031 XM_011530730 XP_011529032 XM_011530731 XP_011529033 XM_011530732 XP_011529034 XM_011530733 XP_011529035 XM_011530734 XP_011529036 XM_011530735 XP_011529037 XM_011530736 XP_011529038 XM_011530737 XP_011529039 XM_011530738 XP_011529040 XM_011530739 XP_011529041 XM_011530740 XP_011529042 NM_001242898 NP_001229827 NM_001242899 NP_001229828 NM_001242900 NP_001229829 NM_014678 NP_055493
|
| Function |
Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. {ECO:0000269|PubMed:16769727}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:16769727}.
|
| Tissue Specificity |
Ubiquitously expressed with strongest expression in the testis followed by liver, heart, kidney, brain and placenta. {ECO:0000269|PubMed:16769727}.
|