Gene Symbol | Nelfcd |
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Entrez Gene | 57314 |
Alt Symbol | 2410003I03Rik, C77797, Th1, Th1l |
Species | Mouse |
Gene Type | protein-coding |
Description | negative elongation factor complex member C/D, Th1l |
Other Description | NELF-D|TH1 homolog|TH1-like homolog|TH1-like protein|negative elongation factor D|trihydrophobin 1 homolog |
Swissprots | Q922L6 Q9QXD0 Q9QXC8 A2AQ05 Q9QXC9 |
Accessions | EDL06676 Q922L6 AJ238741 CAB65252 AJ238742 CAB65253 AJ238743 CAB65254 AK010360 BAB26880 AK049418 BAC33744 AK159866 BAE35440 AK178814 AK182217 AK182268 AK184518 AK187423 AK206914 BC006959 AAH06959 BC031747 AAH31747 XM_006499946 XP_006500009 NM_020580 NP_065605 |
Function | Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. |
NELF-D siRNA (m) - sc-149908 from Santa Cruz Biotechnology
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NELF-D shRNA Plasmid (m) - sc-149908-SH from Santa Cruz Biotechnology
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NELF-D shRNA (m) Lentiviral Particles - sc-149908-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU168171 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN42785 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND42785 from Sigma-Aldrich
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NELFCD siRNA (Mouse) - CRM5998 from Cohesion Biosciences
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NELF-D CRISPR/Cas9 KO Plasmid (m) - sc-437308 from Santa Cruz Biotechnology
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NELF-D HDR Plasmid (m) - sc-437308-HDR from Santa Cruz Biotechnology
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NELF-D Double Nickase Plasmid (m) - sc-437308-NIC from Santa Cruz Biotechnology
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NELF-D Double Nickase Plasmid (m2) - sc-437308-NIC-2 from Santa Cruz Biotechnology
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NELF-D CRISPR Activation Plasmid (m) - sc-437308-ACT from Santa Cruz Biotechnology
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NELF-D CRISPR Activation Plasmid (m2) - sc-437308-ACT-2 from Santa Cruz Biotechnology
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NELF-D Lentiviral Activation Particles (m) - sc-437308-LAC from Santa Cruz Biotechnology
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NELF-D Lentiviral Activation Particles (m2) - sc-437308-LAC-2 from Santa Cruz Biotechnology
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shRNA set against Mouse TH1L (NM_020580.3) - SHH426648 from Creative biogene
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NELFCD shRNA Plasmid (Mouse) - CHM5998 from Cohesion Biosciences
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TH1L miRNA 3'UTR clone - MiUTR1M-11720 from Creative biogene
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