NRAP
| Gene Symbol | NRAP |
|---|---|
| Entrez Gene | 4892 |
| Alt Symbol | N-RAP |
| Species | Human |
| Gene Type | protein-coding |
| Description | nebulin-related anchoring protein |
| Other Description | nebulin-related-anchoring protein |
| Swissprots | Q86TC5 Q86VF6 Q86TD6 Q719H6 Q86VF7 Q5VWI4 Q5VWI3 Q6N026 Q8N8F9 O15500 Q6PDB0 Q6MZK3 Q8TCH0 Q6N059 Q86TE6 Q8N3R6 Q96MG4 Q6NSH8 |
| Accessions | AAC51786 EAW49499 EAW49500 EAW49501 EAW49502 EAW49503 EAW49504 Q86VF7 AF542553 AAQ09536 AK056605 BAB71231 AK056969 BAB71328 AK096875 BAG53387 AK096886 BAC04884 AL831980 CAD89899 AL832025 CAD89910 AL832330 CAD38623 AL832457 CAD89998 AM392642 CAL37520 AM393347 CAL38225 AM393530 CAL38407 AM393795 CAL38670 AY081943 AAL99185 AY177620 AAO47073 AY177621 AAO47074 BC005933 AAH05933 BC017866 AAH17866 BC058825 AAH58825 BC070130 AAH70130 BC126407 AAI26408 BC143751 AAI43752 BX640682 CAE45811 BX640730 CAE45846 BX641052 CAE46027 BX647658 DA564310 F30818 XM_005269864 XP_005269921 XM_005269865 XP_005269922 XM_005269867 XP_005269924 XM_006717870 XP_006717933 XM_011539832 XP_011538134 NM_001261463 NP_001248392 NM_006175 NP_006166 NM_198060 NP_932326 |
| Function | May be involved in anchoring the terminal actin filaments in the myofibril to the membrane and in transmitting tension from the myofibrils to the extracellular matrix. {ECO:0000250|UniProtKB:Q80XB4}. |
| Subcellular Location | Note=Localized at the myotendinous junction in skeletal muscle and at the intercalated disk in cardiac muscle. {ECO:0000269|PubMed:12789664}. |
| Tissue Specificity | Expressed in cardiac and skeletal muscle. {ECO:0000269|PubMed:12789664}. |
N-RAP CRISPR/Cas9 KO Plasmid (h) - sc-408143 from Santa Cruz Biotechnology
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N-RAP HDR Plasmid (h) - sc-408143-HDR from Santa Cruz Biotechnology
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N-RAP Double Nickase Plasmid (h) - sc-408143-NIC from Santa Cruz Biotechnology
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N-RAP Double Nickase Plasmid (h2) - sc-408143-NIC-2 from Santa Cruz Biotechnology
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N-RAP CRISPR Activation Plasmid (h) - sc-408143-ACT from Santa Cruz Biotechnology
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N-RAP CRISPR Activation Plasmid (h2) - sc-408143-ACT-2 from Santa Cruz Biotechnology
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N-RAP Lentiviral Activation Particles (h) - sc-408143-LAC from Santa Cruz Biotechnology
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N-RAP Lentiviral Activation Particles (h2) - sc-408143-LAC-2 from Santa Cruz Biotechnology
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N-RAP siRNA (h) - sc-90390 from Santa Cruz Biotechnology
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N-RAP shRNA Plasmid (h) - sc-90390-SH from Santa Cruz Biotechnology
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N-RAP shRNA (h) Lentiviral Particles - sc-90390-V from Santa Cruz Biotechnology
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NRAP RNAi - H00004892-R01 from Novus Biologicals
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NRAP RNAi - H00004892-R02 from Novus Biologicals
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MISSION® esiRNA - EHU071771 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15500 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15500 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00072 from Sigma-Aldrich
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NRAP siRNA (Human) - CRH3251 from Cohesion Biosciences
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shRNA set against Human NRAP (NM_198060.3) - SHH354912 from Creative biogene
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NRAP shRNA Plasmid (Human) - CHH3251 from Cohesion Biosciences
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NRAP miRNA 3'UTR clone - MiUTR3H-05373 from Creative biogene
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NRAP miRNA 3'UTR clone - MiUTR3H-05374 from Creative biogene
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