| Gene Symbol |
TPO
|
| Entrez Gene |
7173
|
| Alt Symbol |
MSA, TDH2A, TPX
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
thyroid peroxidase
|
| Other Description |
thyroid microsomal antigen|thyroperoxidase
|
| Swissprots |
Q8NF94 Q8IUL0 P09934 Q8NF95 P07202 Q8NF96 Q8TCI9 P09935 Q8NF97
|
| Accessions |
AAA97517 AAB23676 AAB23677 AAD14120 AAX82037 AAX93261 AAY16985 EAX01087 EAX01088 EAX01089 EAX01090 EAX01091 P07202 AB208960 BAD92197 AF439430 AAL74416 AF533528 AAN04471 AF533529 AAN04472 AF533530 AAN04473 AF533531 AAN04474 AK309868 AW874082 AY136822 AAN11302 BC063107 AAH63107 BC095448 AAH95448 BE046044 CB986756 CD608890 DA958481 J02969 AAA61215 J02970 AAA61216 M17755 AAA61217 M55702 AAA61218 X17358 CAA35235 Y00406 CAA68467 XM_011510379 XP_011508681 XM_011510380 XP_011508682 XM_011510381 XP_011508683 XM_011510382 XP_011508684 XR_922681 NM_000547 NP_000538 NM_001206744 NP_001193673 NM_001206745 NP_001193674 NM_175719 NP_783650 NM_175721 NP_783652 NM_175722 NP_783653 NM_175720
|
| Function |
Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Top Pathways |
Autoimmune thyroid disease, Thyroid hormone synthesis, Tyrosine metabolism
|
