| Gene Symbol |
GFM1
|
| Entrez Gene |
85476
|
| Alt Symbol |
COXPD1, EFG, EFG1, EFGM, EGF1, GFM, hEFG1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
G elongation factor, mitochondrial 1
|
| Other Description |
G translation elongation factor, mitochondrial|elongation factor G, mitochondrial|mitochondrial elongation factor G|mitochondrial elongation factor G1
|
| Swissprots |
Q96T39 Q6GTN2 B3KRW1 Q96RP9 B2RCB9 A6NCI9
|
| Accessions |
ADP90694 ADP90695 ADP90696 ADP90697 ADP90698 ADP90699 ADP90700 ADP90701 ADP90702 ADP90703 ADP90704 ADP90705 ADP90706 ADP90707 ADP90708 ADP90709 ADP90710 ADP90711 ADP90712 ADP90713 ADP90714 ADP90715 ADP90716 ADP90717 ADP90718 ADP90719 ADP90720 ADP90721 ADP90722 ADP90723 ADP90724 ADP90725 ADP90726 ADP90727 ADP90728 ADP90729 ADP90730 ADP90731 ADP90732 ADP90733 EAW78677 EAW78678 EAW78679 EAW78680 EAW78681 EAW78682 Q96RP9 AF309777 AAK58877 AF367998 AAK53402 AK000780 AK022724 BAB14205 AK023694 AK092293 BAG52523 AK315031 BAG37516 BC049210 AAH49210 XM_006713795 XP_006713858 XM_011513247 XP_011511549 NM_001308164 NP_001295093 NM_001308166 NP_001295095 NM_024996 NP_079272
|
| Function |
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A- site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. {ECO:0000255|HAMAP-Rule:MF_03061, ECO:0000269|PubMed:19716793}.
|
| Subcellular Location |
Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03061}.
|
![Western Blot: GFM1 Overexpression Lysate (Adult Normal) [NBP2-06244] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GFM1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9492_GFM1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06244-img0001.jpg)