| Gene Symbol | CYP11A1 |
|---|---|
| Entrez Gene | 1583 |
| Alt Symbol | CYP11A, CYPXIA1, P450SCC |
| Species | Human |
| Gene Type | protein-coding |
| Description | cytochrome P450, family 11, subfamily A, polypeptide 1 |
| Other Description | cholesterol 20-22 desmolase|cholesterol monooxygenase (side-chain cleaving)|cholesterol side-chain cleavage enzyme, mitochondrial|cytochrome P450 11A1|cytochrome P450(scc)|cytochrome P450, subfamily XIA (cholesterol side chain cleavage)|cytochrome P450C11A1|steroid 20-22-lyase |
| Swissprots | Q15081 A8K8D5 P05108 Q8N1A7 G3XAD7 Q16805 B3KPU8 |
| Accessions | ABC86898 CAA28965 CAA32471 EAW99341 EAW99342 P05108 AI149078 AK056794 BAG51810 AK225715 AK292300 BAF84989 AK292301 BAF84990 AK293204 BAG56744 AK293211 BAG56751 AK300178 BAG61957 AK310362 AY603498 BC032329 AAH32329 BX398579 DA010417 DQ891578 ABM82504 DQ894771 ABM85697 M14565 AAA52162 M28253 AAA36404 NM_000781 NP_000772 NM_001099773 NP_001093243 |
| Function | Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone. {ECO:0000269|PubMed:21636783}. |
| Subcellular Location | Mitochondrion membrane. |
| Top Pathways | Steroid hormone biosynthesis, Ovarian steroidogenesis |