POLG

Gene Symbol POLG
Entrez Gene 5428
Alt Symbol MDP1, MIRAS, MTDPS4A, MTDPS4B, PEO, POLG1, POLGA, SANDO, SCAE
Species Human
Gene Type protein-coding
Description polymerase (DNA directed), gamma
Other Description DNA polymerase subunit gamma-1|PolG-alpha|mitochondrial DNA polymerase catalytic subunit
Swissprots Q8NFM2 Q92515 P54098
Accessions AAB18268 AAM77583 AAR32994 ABB89206 ABB89207 ADP90854 ADP90855 ADP90856 ADP90857 ADP90858 ADP90859 ADP90860 ADP90861 ADP90862 ADP90863 ADP90864 ADP90865 ADP90866 ADP90867 ADP90868 ADP90869 ADP90870 ADP90871 ADP90872 ADP90873 ADP90874 ADP90875 ADP90876 ADP90877 ADP90878 ADP90879 ADP90880 ADP90881 ADP90882 ADP90883 ADP90884 ADP90885 ADP90886 ADP90887 ADP90888 ADP90889 ADP90890 ADP90891 ADP90892 ADP90893 EAX02045 EAX02046 EAX02047 P54098 AK130624 AK291281 BAF83970 AL110092 AW015913 BC042571 AAH42571 BC050559 AAH50559 D84103 BAA12223 DQ578997 DQ599934 U60325 AAC50712 X98093 CAA66719 NM_001126131 NP_001119603 NM_002693 NP_002684
Function Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:18063578}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269|PubMed:18063578}.

SignalSilence ® DNA Polymerase γ siRNA I - 13573 from Cell Signaling Technology

Category siRNA
Prices $249.00
Sizes 300 µl (3 nmol)
Western blot analysis of extracts from 293T cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-) or SignalSilence ® DNA Polymerase γ siRNA I (+), using DNA Polymerase γ (D1Y6R) Rabbit mAb #13609 (upper) or α-Actinin (D6F6) XP ® Rabbit mAb #6487 (lower). The DNA Polymerase γ (D1Y6R) Rabbit mAb confirms silencing of DNA polymerase γ expression, while the α-Actinin (D6F6) XP ® Rabbit mAb is used as a loading control.

DNA pol γ CRISPR/Cas9 KO Plasmid (h) - sc-401870 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNA pol γ HDR Plasmid (h) - sc-401870-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNA pol γ Double Nickase Plasmid (h) - sc-401870-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNA pol γ Double Nickase Plasmid (h2) - sc-401870-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNA pol γ CRISPR Activation Plasmid (h) - sc-401870-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNA pol γ CRISPR Activation Plasmid (h2) - sc-401870-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNA pol γ Lentiviral Activation Particles (h) - sc-401870-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNA pol γ Lentiviral Activation Particles (h2) - sc-401870-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNA pol γ siRNA (h) - sc-37775 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DNA pol γ shRNA Plasmid (h) - sc-37775-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DNA pol γ shRNA (h) Lentiviral Particles - sc-37775-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DNA Polymerase gamma RNAi - H00005428-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU013531 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17098 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17098 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03730 from Sigma-Aldrich

Category miRNA

POLG siRNA (Human) - CRH3631 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human POLG (NM_002693.2) - SHH379212 from Creative biogene

Category siRNA
Species Reactivities Human

Human POLG siRNA - orb264133 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

POLG shRNA Plasmid (Human) - CHH3631 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

POLG miRNA 3'UTR clone - MiUTR3H-01791 from Creative biogene

Species Reactivities Human

POLG miRNA 3'UTR clone - MiUTR3H-01792 from Creative biogene

Species Reactivities Human
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