Gene Symbol | PQLC2 |
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Entrez Gene | 54896 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | PQ loop repeat containing 2 |
Other Description | PQ-loop repeat-containing protein 2|lysosomal amino acid transporter 1 homolog |
Swissprots | B3KWQ5 Q6ZP29 Q9NXC7 Q6ZP27 Q6ZMJ3 |
Accessions | EAW94882 EAW94883 EAW94884 EAW94885 EAW94886 EAW94887 Q6ZP29 AK000327 BAA91088 AK125580 BAG54217 AK130171 BAC85296 AK130175 BAC85298 AK172745 BAD18732 BC015324 AAH15324 DA202894 DA560373 JF432591 ADZ15808 XM_005245916 XP_005245973 XM_006710710 XP_006710773 XM_006710711 XP_006710774 XM_011541634 XP_011539936 XR_946677 XR_946678 NM_001040125 NP_001035214 NM_001040126 NP_001035215 NM_001287531 NP_001274460 NM_017765 NP_060235 NR_109848 |
Function | Amino acid transporter that specifically mediates the pH-dependent export of the cationic amino acids arginine, histidine and lysine from lysosomes. {ECO:0000269|PubMed:22822152, ECO:0000269|PubMed:23169667}. |
Subcellular Location | Lysosome membrane {ECO:0000269|PubMed:22822152}; Multi-pass membrane protein {ECO:0000269|PubMed:22822152}. |
PQLC2 CRISPR/Cas9 KO Plasmid (h) - sc-412374 from Santa Cruz Biotechnology
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PQLC2 HDR Plasmid (h) - sc-412374-HDR from Santa Cruz Biotechnology
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PQLC2 Double Nickase Plasmid (h) - sc-412374-NIC from Santa Cruz Biotechnology
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PQLC2 Double Nickase Plasmid (h2) - sc-412374-NIC-2 from Santa Cruz Biotechnology
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PQLC2 CRISPR Activation Plasmid (h) - sc-412374-ACT from Santa Cruz Biotechnology
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PQLC2 CRISPR Activation Plasmid (h2) - sc-412374-ACT-2 from Santa Cruz Biotechnology
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PQLC2 Lentiviral Activation Particles (h) - sc-412374-LAC from Santa Cruz Biotechnology
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PQLC2 Lentiviral Activation Particles (h2) - sc-412374-LAC-2 from Santa Cruz Biotechnology
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PQLC2 siRNA (h) - sc-78805 from Santa Cruz Biotechnology
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PQLC2 shRNA Plasmid (h) - sc-78805-SH from Santa Cruz Biotechnology
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PQLC2 shRNA (h) Lentiviral Particles - sc-78805-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU022221 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17331 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17331 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05697 from Sigma-Aldrich
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PQLC2 siRNA (Human) - CRJ0305 from Cohesion Biosciences
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shRNA set against Human PQLC2 (NM_017765.2) - SHH381824 from Creative biogene
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shRNA set against Human PQLC2(NM_001040126.1) - SHR136410 from Creative biogene
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shRNA set against Human PQLC2(NM_001040125.1) - SHR136428 from Creative biogene
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PQLC2 shRNA Plasmid (Human) - CHJ0305 from Cohesion Biosciences
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PQLC2 miRNA 3'UTR clone - MiUTR1H-08206 from Creative biogene
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PQLC2 miRNA 3'UTR clone - MiUTR1H-08207 from Creative biogene
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PQLC2 miRNA 3'UTR clone - MiUTR3H-13384 from Creative biogene
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