Gene Symbol | PFKP |
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Entrez Gene | 5214 |
Alt Symbol | ATP-PFK, PFK-C, PFK-P, PFKF |
Species | Human |
Gene Type | protein-coding |
Description | phosphofructokinase, platelet |
Other Description | 6-phosphofructokinase type C|6-phosphofructokinase, platelet type|ATP-PFK|ATP-dependent 6-phosphofructokinase, platelet type|Phosphofructokinase, platelet type|phosphofructo-1-kinase isozyme C|phosphofructokinase 1|phosphohexokinase |
Swissprots | Q5VSR7 B3KS15 Q5VSR8 Q01813 |
Accessions | EAW86495 EAW86496 EAW86497 Q01813 AA622586 AK092597 BAG52577 AK097692 BAG53515 AK126153 AK128373 AK129843 AK130767 AK291841 BAF84530 AK308003 AK308226 AK309692 AL521453 BC002536 AAH02536 BC021698 AAH21698 BC029138 AAH29138 BC043156 AAH43156 BU737488 CD365858 D21863 BAA21891 D25328 BAA04998 DQ895147 ABM86073 EU176319 ABW03770 M64784 AAA36435 XM_005252465 XP_005252522 XM_005252466 XP_005252523 XM_005252467 XP_005252524 XM_006717449 XP_006717512 NM_001242339 NP_001229268 NM_002627 NP_002618 |
Function | Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. |
Subcellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03184}. |
Top Pathways | Central carbon metabolism in cancer, AMPK signaling pathway, Glycolysis / Gluconeogenesis, RNA degradation, Pentose phosphate pathway |
SignalSilence ® PFKP siRNA I - 12649 from Cell Signaling Technology
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PFKP CRISPR/Cas9 KO Plasmid (h) - sc-402989 from Santa Cruz Biotechnology
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PFKP HDR Plasmid (h) - sc-402989-HDR from Santa Cruz Biotechnology
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PFKP Double Nickase Plasmid (h) - sc-402989-NIC from Santa Cruz Biotechnology
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PFKP Double Nickase Plasmid (h2) - sc-402989-NIC-2 from Santa Cruz Biotechnology
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PFKP CRISPR Activation Plasmid (h) - sc-402989-ACT from Santa Cruz Biotechnology
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PFKP CRISPR Activation Plasmid (h2) - sc-402989-ACT-2 from Santa Cruz Biotechnology
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PFKP Lentiviral Activation Particles (h) - sc-402989-LAC from Santa Cruz Biotechnology
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PFKP Lentiviral Activation Particles (h2) - sc-402989-LAC-2 from Santa Cruz Biotechnology
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PFKP siRNA (h) - sc-106401 from Santa Cruz Biotechnology
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PFKP shRNA Plasmid (h) - sc-106401-SH from Santa Cruz Biotechnology
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PFKP shRNA (h) Lentiviral Particles - sc-106401-V from Santa Cruz Biotechnology
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PFKP RNAi - H00005214-R03 from Novus Biologicals
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MISSION® esiRNA - EHU016671 from Sigma-Aldrich
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MISSION® siRNA - SIHK1593 from Sigma-Aldrich
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MISSION® siRNA - SIHK1594 from Sigma-Aldrich
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MISSION® siRNA - SIHK1592 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16660 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16660 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01304 from Sigma-Aldrich
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PFKP siRNA (Human) - CRH3484 from Cohesion Biosciences
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shRNA set against Human PFKP (NM_002627.4) - SHH373980 from Creative biogene
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Human PFKP siRNA - orb263986 from Biorbyt
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PFKP shRNA Plasmid (Human) - CHH3484 from Cohesion Biosciences
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PFKP miRNA 3'UTR clone - MiUTR3H-01723 from Creative biogene
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