Gene Symbol | SFTPB |
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Entrez Gene | 6439 |
Alt Symbol | PSP-B, SFTB3, SFTP3, SMDP1, SP-B |
Species | Human |
Gene Type | protein-coding |
Description | surfactant protein B |
Other Description | 18 kDa pulmonary-surfactant protein|6 kDa protein|pulmonary surfactant-associated protein B|pulmonary surfactant-associated proteolipid SPL(Phe) |
Swissprots | P07988 Q96R04 |
Accessions | AAB59541 AAK77913 CAJ18771 EAW99487 EAW99488 EAW99489 P07988 AB439563 AB439564 AB439565 AB439566 AK303817 BAG64767 AK314947 BAG37452 AL548140 AW204600 BC032785 AAH32785 BG482852 BI821350 BM989941 CA435153 CA437348 CA439044 DQ317589 ABC59511 HQ447860 ADQ32344 J02761 AAA60212 M16764 AAA88099 M19097 AAA36628 XM_005264487 XP_005264544 XM_005264488 XP_005264545 XM_005264490 XP_005264547 NM_000542 NP_000533 NM_198843 NP_942140 |
Function | Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. |
Subcellular Location | Secreted, extracellular space, surface film. |
SP-B CRISPR/Cas9 KO Plasmid (h) - sc-401992 from Santa Cruz Biotechnology
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SP-B HDR Plasmid (h) - sc-401992-HDR from Santa Cruz Biotechnology
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SP-B Double Nickase Plasmid (h) - sc-401992-NIC from Santa Cruz Biotechnology
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SP-B Double Nickase Plasmid (h2) - sc-401992-NIC-2 from Santa Cruz Biotechnology
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SP-B CRISPR Activation Plasmid (h) - sc-401992-ACT from Santa Cruz Biotechnology
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SP-B CRISPR Activation Plasmid (h2) - sc-401992-ACT-2 from Santa Cruz Biotechnology
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SP-B Lentiviral Activation Particles (h) - sc-401992-LAC from Santa Cruz Biotechnology
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SP-B Lentiviral Activation Particles (h2) - sc-401992-LAC-2 from Santa Cruz Biotechnology
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SP-B siRNA (h) - sc-36537 from Santa Cruz Biotechnology
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SP-B shRNA Plasmid (h) - sc-36537-SH from Santa Cruz Biotechnology
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SP-B shRNA (h) Lentiviral Particles - sc-36537-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU123801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19210 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1307 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19210 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09854 from Sigma-Aldrich
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SFTPB siRNA (Human) - CRH4350 from Cohesion Biosciences
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SFTPB - MBS8230667 from MyBioSource
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shRNA set against Human SFTPB (NM_000542.3) - SHH406064 from Creative biogene
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SFTPB shRNA Plasmid (Human) - CHH4350 from Cohesion Biosciences
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SFTPB miRNA 3'UTR clone - MiUTR4H-TG08000 from Creative biogene
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