Gene Symbol | SSR1 |
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Entrez Gene | 6745 |
Alt Symbol | TRAPA |
Species | Human |
Gene Type | protein-coding |
Description | signal sequence receptor, alpha |
Other Description | SSR alpha subunit|SSR-alpha|TRAP alpha|TRAP-alpha|signal sequence receptor subunit alpha|translocon-associated protein alpha subunit|translocon-associated protein subunit alpha |
Swissprots | Q9TNQ8 Q96IA2 Q53GX2 Q8NBH9 Q9UN49 Q53H19 A8K685 P43307 Q6IB43 Q5TAM3 |
Accessions | EAW55202 EAW55203 EAW55204 P43307 AF156965 AAD48778 AJ420492 AK024294 AK025753 AK026687 AK075562 BAC11701 AK222762 BAD96482 AK222809 BAD96529 AK291550 BAF84239 AK312653 BAG35536 AL550910 BC007710 AAH07710 BI553058 BM685131 BQ216448 BT007387 AAP36051 CA424805 CR456961 CAG33242 CR936719 DC384883 DQ892751 ABM83677 EU176743 ABW03544 Z12830 CAA78290 NM_001292008 NP_001278937 NM_003144 NP_003135 NR_120448 |
Function | TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins. |
Subcellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein. |
Top Pathways | Protein processing in endoplasmic reticulum |
TRAP-α CRISPR/Cas9 KO Plasmid (h) - sc-405533 from Santa Cruz Biotechnology
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TRAP-α HDR Plasmid (h) - sc-405533-HDR from Santa Cruz Biotechnology
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TRAP-α Double Nickase Plasmid (h) - sc-405533-NIC from Santa Cruz Biotechnology
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TRAP-α Double Nickase Plasmid (h2) - sc-405533-NIC-2 from Santa Cruz Biotechnology
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TRAP-α CRISPR Activation Plasmid (h) - sc-405533-ACT from Santa Cruz Biotechnology
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TRAP-α CRISPR Activation Plasmid (h2) - sc-405533-ACT-2 from Santa Cruz Biotechnology
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TRAP-α Lentiviral Activation Particles (h) - sc-405533-LAC from Santa Cruz Biotechnology
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TRAP-α Lentiviral Activation Particles (h2) - sc-405533-LAC-2 from Santa Cruz Biotechnology
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TRAP-α siRNA (h) - sc-63153 from Santa Cruz Biotechnology
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TRAP-α shRNA Plasmid (h) - sc-63153-SH from Santa Cruz Biotechnology
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TRAP-α shRNA (h) Lentiviral Particles - sc-63153-V from Santa Cruz Biotechnology
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TRAP alpha RNAi - H00006745-R01 from Novus Biologicals
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MISSION® esiRNA - EHU132121 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20627 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20627 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11239 from Sigma-Aldrich
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SSR1 siRNA (Human) - CRH4608 from Cohesion Biosciences
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SSR1 - MBS8200992 from MyBioSource
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shRNA set against Human SSR1 (NM_003144.3) - SHH418484 from Creative biogene
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Human SSR1 siRNA - orb265110 from Biorbyt
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SSR1 shRNA Plasmid (Human) - CHH4608 from Cohesion Biosciences
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