Gene Symbol | TNNI3 |
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Entrez Gene | 7137 |
Alt Symbol | CMD1FF, CMD2A, CMH7, RCM1, TNNC1, cTnI |
Species | Human |
Gene Type | protein-coding |
Description | troponin I type 3 (cardiac) |
Other Description | cardiomyopathy, dilated 2A (autosomal recessive)|troponin I, cardiac muscle |
Swissprots | P19429 |
Accessions | ABC46406 ABV44804 ABV44805 ABV44806 ABV48787 ABV48788 ABX82506 ABX82507 ABX82508 ABX82509 ABX82510 ADL14492 CAA62301 P19429 AK223451 BAD97171 BC096165 AAH96165 BC096166 AAH96166 BC096167 AAH96167 BC099631 AAH99631 BT019517 AAV38324 CR541985 CAG46782 CR542012 CAG46809 EU747720 ACH92818 M64247 AAA16157 X54163 CAA38102 NM_000363 NP_000354 |
Function | Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. |
Top Pathways | Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy, Adrenergic signaling in cardiomyocytes, cAMP signaling pathway |
Troponin I-C CRISPR/Cas9 KO Plasmid (h) - sc-400466 from Santa Cruz Biotechnology
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Troponin I-C HDR Plasmid (h) - sc-400466-HDR from Santa Cruz Biotechnology
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Troponin I-C Double Nickase Plasmid (h) - sc-400466-NIC from Santa Cruz Biotechnology
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Troponin I-C Double Nickase Plasmid (h2) - sc-400466-NIC-2 from Santa Cruz Biotechnology
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Troponin I-C CRISPR Activation Plasmid (h) - sc-400466-ACT from Santa Cruz Biotechnology
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Troponin I-C CRISPR Activation Plasmid (h2) - sc-400466-ACT-2 from Santa Cruz Biotechnology
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Troponin I-C Lentiviral Activation Particles (h) - sc-400466-LAC from Santa Cruz Biotechnology
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Troponin I-C Lentiviral Activation Particles (h2) - sc-400466-LAC-2 from Santa Cruz Biotechnology
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Troponin I-C siRNA (h) - sc-36738 from Santa Cruz Biotechnology
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Troponin I-C shRNA Plasmid (h) - sc-36738-SH from Santa Cruz Biotechnology
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Troponin I-C shRNA (h) Lentiviral Particles - sc-36738-V from Santa Cruz Biotechnology
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Troponin I Type 3 (cardiac) RNAi - H00007137-R01V from Novus Biologicals
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Troponin I Type 3 (cardiac) RNAi - H00007137-R01 from Novus Biologicals
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Troponin C (cardiac) RNAi - H00007134-R01 from Novus Biologicals
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MISSION® esiRNA - EHU022131 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21786 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21786 from Sigma-Aldrich
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TNNI3 siRNA (Human) - CRH4896 from Cohesion Biosciences
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TNNI3 - MBS8235195 from MyBioSource
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shRNA set against Human TNNI3 (NM_000363.4) - SHH432392 from Creative biogene
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shRNA set against Human TNNI3(NM_000363.4) - SHL086286 from Creative biogene
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Human TNNI3 siRNA - orb265398 from Biorbyt
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TNNI3 shRNA Plasmid (Human) - CHH4896 from Cohesion Biosciences
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TNNI3 miRNA 3'UTR clone - MiUTR1H-10620 from Creative biogene
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