Gene Symbol | TRIP13 |
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Entrez Gene | 9319 |
Alt Symbol | 16E1BP |
Species | Human |
Gene Type | protein-coding |
Description | thyroid hormone receptor interactor 13 |
Other Description | 16E1-BP|HPV16 E1 protein binding protein|HPV16 E1 protein-binding protein|TR-interacting protein 13|TRIP-13|human papillomavirus type 16 E1 protein-binding protein|pachytene checkpoint protein 2 homolog|thyroid receptor interacting protein 13|thyroid receptor-interacting protein 13 |
Swissprots | D3DTC0 O15324 Q15645 C9K0T3 |
Accessions | EAX08185 EAX08186 Q15645 AK310376 BC000404 AAH00404 BC019294 AAH19294 BG722761 BM999741 CR456744 CAG33025 DB443523 EU446745 ABZ92274 L40384 AAC41732 U96131 AAB64095 XM_011514163 XP_011512465 NM_001166260 NP_001159732 NM_004237 NP_004228 |
Function | Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double- strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity). {ECO:0000250}. |
TRIP13 CRISPR/Cas9 KO Plasmid (h) - sc-404006 from Santa Cruz Biotechnology
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TRIP13 HDR Plasmid (h) - sc-404006-HDR from Santa Cruz Biotechnology
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TRIP13 Double Nickase Plasmid (h) - sc-404006-NIC from Santa Cruz Biotechnology
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TRIP13 Double Nickase Plasmid (h2) - sc-404006-NIC-2 from Santa Cruz Biotechnology
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TRIP13 CRISPR Activation Plasmid (h) - sc-404006-ACT from Santa Cruz Biotechnology
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TRIP13 CRISPR Activation Plasmid (h2) - sc-404006-ACT-2 from Santa Cruz Biotechnology
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TRIP13 Lentiviral Activation Particles (h) - sc-404006-LAC from Santa Cruz Biotechnology
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TRIP13 Lentiviral Activation Particles (h2) - sc-404006-LAC-2 from Santa Cruz Biotechnology
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TRIP13 siRNA (h) - sc-91672 from Santa Cruz Biotechnology
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TRIP13 shRNA Plasmid (h) - sc-91672-SH from Santa Cruz Biotechnology
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TRIP13 shRNA (h) Lentiviral Particles - sc-91672-V from Santa Cruz Biotechnology
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Thyroid receptor-interacting protein 13 RNAi - H00009319-R01 from Novus Biologicals
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MISSION® esiRNA - EHU132671 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22030 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22030 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07933 from Sigma-Aldrich
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TRIP13 siRNA (Human) - CRH6165 from Cohesion Biosciences
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TRIP13 - MBS8214464 from MyBioSource
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shRNA set against Human TRIP13 (NM_004237.3) - SHH435212 from Creative biogene
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TRIP13 shRNA Plasmid (Human) - CHH6165 from Cohesion Biosciences
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TRIP13 miRNA 3'UTR clone - MiUTR3H-06868 from Creative biogene
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TRIP13 miRNA 3'UTR clone - MiUTR3H-06869 from Creative biogene
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