Gene Symbol | DSG1 |
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Entrez Gene | 1828 |
Alt Symbol | CDHF4, DG1, DSG, EPKHE, EPKHIA, PPKS1, SPPK1 |
Species | Human |
Gene Type | protein-coding |
Description | desmoglein 1 |
Other Description | cadherin family member 4|desmoglein-1|desmosomal glycoprotein 1|pemphigus foliaceus antigen |
Swissprots | B7Z845 Q02413 |
Accessions | CAA04949 EAX01254 Q02413 AF088042 AF097935 AAC83817 AK302888 BAH13831 BC148374 AAI48375 BC153001 AAI53002 BX476267 CU456411 X56654 CAA39976 NM_001942 NP_001933 |
Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, desmosome. |
Tissue Specificity | Epidermis, tongue, tonsil and esophagus. |
Top Pathways | Staphylococcus aureus infection |
dsg1 CRISPR/Cas9 KO Plasmid (h) - sc-401442 from Santa Cruz Biotechnology
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dsg1 HDR Plasmid (h) - sc-401442-HDR from Santa Cruz Biotechnology
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dsg1 Double Nickase Plasmid (h) - sc-401442-NIC from Santa Cruz Biotechnology
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dsg1 Double Nickase Plasmid (h2) - sc-401442-NIC-2 from Santa Cruz Biotechnology
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dsg1 CRISPR Activation Plasmid (h) - sc-401442-ACT from Santa Cruz Biotechnology
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dsg1 CRISPR Activation Plasmid (h2) - sc-401442-ACT-2 from Santa Cruz Biotechnology
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dsg1 Lentiviral Activation Particles (h) - sc-401442-LAC from Santa Cruz Biotechnology
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dsg1 Lentiviral Activation Particles (h2) - sc-401442-LAC-2 from Santa Cruz Biotechnology
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dsg1 siRNA (h) - sc-35224 from Santa Cruz Biotechnology
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dsg1 shRNA Plasmid (h) - sc-35224-SH from Santa Cruz Biotechnology
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dsg1 shRNA (h) Lentiviral Particles - sc-35224-V from Santa Cruz Biotechnology
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Desmoglein-1 RNAi - H00001828-R01 from Novus Biologicals
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MISSION® esiRNA - EHU036261 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7508 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7508 from Sigma-Aldrich
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DSG1 siRNA (Human) - CRH1277 from Cohesion Biosciences
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DSG1 - MBS8213061 from MyBioSource
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dsg1 CRISPR/Cas9 KO Plasmid (h2) - sc-401442-KO-2 from Santa Cruz Biotechnology
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dsg1 HDR Plasmid (h2) - sc-401442-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human DSG1 (NM_001942.2) - SHH281249 from Creative biogene
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Human DSG1 siRNA - orb261779 from Biorbyt
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DSG1 shRNA Plasmid (Human) - CHH1277 from Cohesion Biosciences
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DSG1 miRNA 3'UTR clone - MiUTR1H-03009 from Creative biogene
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