AMPD2

Gene Symbol	AMPD2
Entrez Gene	271
Alt Symbol	PCH9, SPG63
Species	Human
Gene Type	protein-coding
Description	adenosine monophosphate deaminase 2
Other Description	AMP deaminase 2\|AMPD\|adenosine monophosphate deaminase 2 (isoform L)
Swissprots	Q9UDX8 Q96IA1 Q14857 Q16688 Q5T695 Q01433 Q16729 Q9UMU4 B4DZI5 Q5T693 B4DK50 Q9UDX9 Q16686 Q14856 Q16687 E9PNG0
Accessions	AAA62126 AAA62127 AAB06511 AAC50309 AAD56302 AAD56303 EAW56396 EAW56397 EAW56398 EAW56399 EAW56400 EAW56401 Q01433 AK025706 AK296394 BAG59062 AK302939 BAG64097 AK308907 AK314494 BAG37094 BC007711 AAH07711 BC030217 BC075844 AAH75844 DA444620 DA558264 DC410161 S47833 AAA11725 U16267 AAC50306 U16268 AAC50307 U16270 AAC50308 XM_005270752 XP_005270809 XM_011541247 XP_011539549 XM_011541248 XP_011539550 XR_946607 NM_001257360 NP_001244289 NM_001257361 NP_001244290 NM_001308170 NP_001295099 NM_004037 NP_004028 NM_139156 NP_631895 NM_203404 NP_981949
Function	AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle. {ECO:0000269\|PubMed:23911318}.
Tissue Specificity	Highly expressed in cerebellum. Three isoforms are present in mammals: AMP deaminase 1 is the predominant form in skeletal muscle; AMP deaminase 2 predominates in smooth muscle, non-muscle tissue, embryonic muscle and undifferentiated myoblasts; AMP deaminase 3 is found in erythrocytes. {ECO:0000269\|PubMed:23911318}.
Top Pathways	Purine metabolism

AMPD2 (G-19) - sc-324825 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

AMPD2 (S-20) - sc-324824 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

AMPD2 (QQ13) - sc-100504 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	50 µg/0.5 ml
Host	Mouse
Clonality	Monoclonal

AMPD2 (QQ13): sc-100504. Western blot analysis of AMPD2 expression in HeLa nuclear extract.

Anti-AMPD2 antibody - ab137598 from Abcam

Prices	$370.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AMPD2 antibody (ab137598) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-AMPD2 antibody - ab135966 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

ICC/IF image of ab135966 stained HepG2 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab135966 at 5 µg/mL overnight at +4°C. The secondary antibody (green) was DyLight® 488 Goat anti-Rabbit IgG (H+L) (ab96899) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-AMPD2 antibody - ab95266 from Abcam

Prices	$359.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-AMPD2 antibody (ab95266) at 1/50 dilution + K562 cell line lysate at 12.5 µgObserved band size : 101 kDa (why is the actual band size different from the predicted?)

Anti-AMPD2 antibody - ab54791 from Abcam

Prices	$450.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal

Anti-AMPD2 antibody - ab128678 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AMPD2 antibody (ab128678) at 1 µg/ml + HeLa cell lysate at 10 µgSecondaryGoat anti-Rabbit IgG HRP

Anti-AMPD2 antibody - N-terminal - ab134249 from Abcam

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AMPD2 antibody - N-terminal (ab134249) at 1 µg/ml + MCF7 cell lysate at 10 µg

Anti-AMPD2 Antibody - LS-C309440 from LifeSpan Bioscience

Prices	$475.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AMPD2 Antibody (clone 2G8) - LS-C139411 from LifeSpan Bioscience

Prices	$355.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	2G8

Western blot of AMPD2 expression in transfected 293T cell line by AMPD2 monoclonal antibody (M04), clone 2G8.

Anti-AMPD2 Antibody (aa118-167) - LS-C200123 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of the lysates from HeLa cells using AMPD2 antibody.

Anti-AMPD2 Antibody (clone 6A8) - LS-C139430 from LifeSpan Bioscience

Prices	$355.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	6A8

AMPD2 monoclonal antibody (M09), clone 6A8. Western blot of AMPD2 expression in HeLa.

Anti-AMPD2 Antibody (aa187-217) - LS-C156316 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Formalin-fixed and paraffin-embedded human skeletal muscle reacted with AMPD2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-AMPD2 Antibody (aa244-293) - LS-C151776 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-AMPD2 Antibody (aa104-153) - LS-C151777 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

AMPD2 Antibody (2F5) - H00000271-M01 from Novus Biologicals

Prices	$315.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	2F5

Western Blot: AMPD2 Antibody (2F5) [H00000271-M01] - AMPD2 monoclonal antibody (M01), clone 2F5. Western Blot analysis of AMPD2 expression in Raw 264.7 ( Cat # L024V1 ).

AMPD2 Antibody (2F5) - H00000271-M01A from Novus Biologicals

Prices	$359.00
Sizes	200 µl
Host	Mouse
Clonality	Monoclonal
Clone	2F5

AMPD2 Antibody - NBP1-33698 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

AMPD2 Antibody (6A8) - H00000271-M09 from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	6A8

Western Blot: AMPD2 Antibody (6A8) [H00000271-M09] - Analysis of AMPD2 expression in human liver.

AMPD2 Antibody (2G8) - H00000271-M04 from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	2G8

Western Blot: AMPD2 Antibody (2G8) [H00000271-M04] - Analysis of AMPD2 expression in transfected 293T cell line by AMPD2 monoclonal antibody (M04A), clone 2G8. Lane 1: AMPD2 transfected lysatE (92.1 KDa). Lane 2: Non-transfected lysate.

AMPD2 Antibody - H00000271-B01 from Novus Biologicals

Prices	$349.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot: AMPD2 Antibody [H00000271-B01] - analysis of AMPD2 expression in transfected 293T cell line by AMPD2 MaxPab polyclonal antibody (B01). Lane 1: AMPD2 transfected lysate (92.10 KDa). Lane 2: Non-transfected lysate.

AMPD2 Antibody (3C5) - H00000271-M05 from Novus Biologicals

Prices	$349.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	3C5

Western Blot: AMPD2 Antibody (3C5) [H00000271-M05] - analysis of AMPD2 expression in transfected 293T cell line by AMPD2 monoclonal antibody (M05), clone 3C5. Lane 1: AMPD2 transfected lysate (92.1 KDa). Lane 2: Non-transfected lysate.

AMPD2 Antibody (6A8) - H00000271-M09A from Novus Biologicals

Prices	$349.00
Sizes	200 µl
Host	Mouse
Clonality	Monoclonal
Clone	6A8

AMPD2 Antibody (2G8) - H00000271-M04A from Novus Biologicals

Prices	$359.00
Sizes	200 µl
Host	Mouse
Clonality	Monoclonal
Clone	2G8

Western Blot: AMPD2 Antibody (2G8) [H00000271-M04A] - Analysis of AMPD2 expression in transfected 293T cell line by AMPD2 monoclonal antibody (M04A), clone 2G8. Lane 1: AMPD2 transfected lysatE (92.1 KDa). Lane 2: Non-transfected lysate.

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