| Gene Symbol | CEP290 |
|---|---|
| Entrez Gene | 282707 |
| Alt Symbol | - |
| Species | Bovine |
| Gene Type | protein-coding |
| Description | centrosomal protein 290kDa |
| Other Description | centrosomal protein of 290 kDa|nephrocystin-6 |
| Swissprots | Q0P567 Q9TU23 |
| Accessions | DAA30091 Q9TU23 AF176816 AAF00990 BC120445 AAI20446 XM_005206047 XP_005206104 XM_010804766 XP_010803068 XM_010804767 XP_010803069 XM_010804768 XP_010803070 XM_010804769 XP_010803071 XM_010804770 XP_010803072 NM_174722 NP_777147 |
| Function | Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes (By similarity). Could be required for ciliogenesis (By similarity). {ECO:0000250|UniProtKB:O15078, ECO:0000250|UniProtKB:Q6A078}. |
| Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000250}. Nucleus {ECO:0000250}. Cell projection, cilium {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Note=Displaced from centriolar satellites in response to cellular stress, such as ultraviolet light (UV) radiation or heat shock. Connecting cilium of photoreceptor cells, base of cilium in kidney intramedullary collecting duct cells. Localizes at the transition zone, a region between the basal body and the ciliary axoneme (By similarity). {ECO:0000250}. |
Centrosomal protein of 290 kDa (CEP290), Bovine, ELISA Kit - E11C0951 from ARP American Research Products
|
||||||
Centrosomal protein of 290 kDa (CEP290), Bovine, ELISA Kit - E11C1618 from ARP American Research Products
|
||||||
Centrosomal protein of 290 kDa (CEP290), ELISA Kit - MBS287772 from MyBioSource
|
||||||