| Gene Symbol | Mecr |
|---|---|
| Entrez Gene | 29470 |
| Alt Symbol | Nrbf1 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | mitochondrial trans-2-enoyl-CoA reductase |
| Other Description | NRBF-1|nuclear receptor binding factor 1|nuclear receptor-binding factor 1|trans-2-enoyl-CoA reductase, mitochondrial |
| Swissprots | F1LPY7 Q9Z311 |
| Accessions | EDL80609 EDL80610 EDL80611 Q9Z311 AB015724 BAA34804 FQ210707 XM_006239009 XP_006239071 NM_017209 NP_058905 |
| Function | Oxidoreductase with a preference for short and medium chain substrates, including trans-2-hexenoyl-CoA (C6), trans-2- decenoyl-CoA (C10), and trans-2-hexadecenoyl-CoA (C16). May play a role in mitochondrial fatty acid synthesis (By similarity). {ECO:0000250}. |
| Subcellular Location | Isoform 1: Mitochondrion {ECO:0000269|PubMed:12654921}. |
| Top Pathways | Fatty acid elongation, Fatty acid metabolism |
CompoZr® Knockout ZFN Kit - CKOZFN57118 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND57118 from Sigma-Aldrich
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MECR siRNA (Rat) - CRR1174 from Cohesion Biosciences
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shRNA set against Rat MECR (NM_017209.1) - SHH339819 from Creative biogene
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shRNA set against Rat Mecr(NM_017209.1) - SHH183269 from Creative biogene
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Rat MECR siRNA - orb296023 from Biorbyt
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MECR shRNA Plasmid (Rat) - CHR1174 from Cohesion Biosciences
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MECR miRNA 3'UTR clone - MiUTR1R-03751 from Creative biogene
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