Gene Symbol | NDUFA11 |
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Entrez Gene | 126328 |
Alt Symbol | B14.7, CI-B14.7 |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa |
Other Description | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11|NADH-ubiquinone oxidoreductase subunit B14.7|complex I B14.7 subunit |
Swissprots | Q86Y39 Q6ZS66 C9JT23 |
Accessions | CAI93622 EAW69131 EAW69132 EAW69133 Q86Y39 AI125604 AI272174 AJ539081 CAD62165 AK127692 BAC87088 AL546175 AY726561 BC069045 AAH69045 BI160094 BP432135 BQ054257 BQ671956 BQ955016 NM_001193375 NP_001180304 NM_175614 NP_783313 NR_034166 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}; Matrix side {ECO:0000250}. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFA11 CRISPR/Cas9 KO Plasmid (h) - sc-414269 from Santa Cruz Biotechnology
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NDUFA11 HDR Plasmid (h) - sc-414269-HDR from Santa Cruz Biotechnology
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NDUFA11 Double Nickase Plasmid (h) - sc-414269-NIC from Santa Cruz Biotechnology
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NDUFA11 Double Nickase Plasmid (h2) - sc-414269-NIC-2 from Santa Cruz Biotechnology
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NDUFA11 CRISPR Activation Plasmid (h) - sc-414269-ACT from Santa Cruz Biotechnology
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NDUFA11 CRISPR Activation Plasmid (h2) - sc-414269-ACT-2 from Santa Cruz Biotechnology
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NDUFA11 Lentiviral Activation Particles (h) - sc-414269-LAC from Santa Cruz Biotechnology
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NDUFA11 Lentiviral Activation Particles (h2) - sc-414269-LAC-2 from Santa Cruz Biotechnology
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NDUFA11 siRNA (h) - sc-97254 from Santa Cruz Biotechnology
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NDUFA11 shRNA Plasmid (h) - sc-97254-SH from Santa Cruz Biotechnology
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NDUFA11 shRNA (h) Lentiviral Particles - sc-97254-V from Santa Cruz Biotechnology
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NDUFA11 RNAi - H00126328-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN15136 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15136 from Sigma-Aldrich
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NDUFA11 siRNA (Human) - CRJ4858 from Cohesion Biosciences
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shRNA set against Human NDUFA11 (NM_175614.4) - SHH350484 from Creative biogene
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Human NDUFA11 siRNA - orb275359 from Biorbyt
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NDUFA11 shRNA Plasmid (Human) - CHJ4858 from Cohesion Biosciences
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NDUFA11 miRNA 3'UTR clone - MiUTR3H-12520 from Creative biogene
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