| Gene Symbol | AFP |
|---|---|
| Entrez Gene | 174 |
| Alt Symbol | AFPD, FETA, HPAFP |
| Species | Human |
| Gene Type | protein-coding |
| Description | alpha-fetoprotein |
| Other Description | alpha-1-fetoprotein|alpha-fetoglobulin |
| Swissprots | P02771 B2RBU3 |
| Accessions | AAA51674 AAA51675 AAB58754 CAA79592 EAX05681 P02771 AF484525 AF484526 AI336986 AK297669 BAG60031 AK297674 BAG60036 AK314817 BAG37340 BC027881 AAH27881 DQ890942 ABM81868 DQ894103 ABM85029 V01514 CAA24758 XM_011531704 XP_011530006 NM_001134 NP_001125 |
| Function | Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Plasma. Synthesized by the fetal liver and yolk sac. |
| Top Pathways | Hippo signaling pathway |