Gene Symbol | POLG2 |
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Entrez Gene | 11232 |
Alt Symbol | HP55, MTPOLB, PEOA4, POLB, POLG-BETA, POLGB |
Species | Human |
Gene Type | protein-coding |
Description | polymerase (DNA directed), gamma 2, accessory subunit |
Other Description | DNA polymerase gamma accessory 55 kDa subunit|DNA polymerase subunit gamma-2, mitochondrial|mitochondrial DNA polymerase accessory subunit|mitochondrial DNA polymerase subunit gamma-2|mitochondrial DNA polymerase, accessory subunit|p55 |
Swissprots | O00419 Q9UHN1 Q9UK94 Q9UK35 Q96GW2 Q0IJ81 |
Accessions | ADP91694 ADP91695 ADP91696 ADP91697 ADP91698 ADP91699 ADP91700 ADP91701 ADP91702 ADP91703 ADP91704 ADP91705 ADP91706 ADP91707 ADP91708 ADP91709 ADP91710 ADP91711 ADP91712 ADP91713 ADP91714 ADP91715 ADP91716 ADP91717 ADP91718 ADP91719 ADP91720 ADP91721 ADP91722 ADP91723 ADP91724 ADP91725 ADP91726 ADP91727 ADP91728 ADP91729 ADP91730 ADP91731 ADP91732 ADP91733 EAW94204 Q9UHN1 AF142992 AAD50382 AF177201 AAD56640 AF184344 AAD56542 AK307801 BC000913 AAH00913 BC009194 AAH09194 BI826587 U94703 AAC51321 XM_006721651 XP_006721714 XR_243630 XR_934357 XR_934358 NM_007215 NP_009146 |
Function | Mitochondrial polymerase processivity subunit. Stimulates the polymerase and exonuclease activities, and increases the processivity of the enzyme. Binds to ss-DNA. |
Subcellular Location | Mitochondrion. |
DNA pol γ2 CRISPR/Cas9 KO Plasmid (h) - sc-407382 from Santa Cruz Biotechnology
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DNA pol γ2 HDR Plasmid (h) - sc-407382-HDR from Santa Cruz Biotechnology
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DNA pol γ2 Double Nickase Plasmid (h) - sc-407382-NIC from Santa Cruz Biotechnology
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DNA pol γ2 Double Nickase Plasmid (h2) - sc-407382-NIC-2 from Santa Cruz Biotechnology
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DNA pol γ2 CRISPR Activation Plasmid (h) - sc-407382-ACT from Santa Cruz Biotechnology
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DNA pol γ2 CRISPR Activation Plasmid (h2) - sc-407382-ACT-2 from Santa Cruz Biotechnology
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DNA pol γ2 Lentiviral Activation Particles (h) - sc-407382-LAC from Santa Cruz Biotechnology
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DNA pol γ2 Lentiviral Activation Particles (h2) - sc-407382-LAC-2 from Santa Cruz Biotechnology
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DNA pol γ2 siRNA (h) - sc-93686 from Santa Cruz Biotechnology
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DNA pol γ2 shRNA Plasmid (h) - sc-93686-SH from Santa Cruz Biotechnology
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DNA pol γ2 shRNA (h) Lentiviral Particles - sc-93686-V from Santa Cruz Biotechnology
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DNA Polymerase beta RNAi - H00005423-R01 from Novus Biologicals
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POLG2 RNAi - H00011232-R01 from Novus Biologicals
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MISSION® esiRNA - EHU065241 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2367 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2367 from Sigma-Aldrich
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POLG2 siRNA (Human) - CRH7698 from Cohesion Biosciences
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DNA pol γ2 CRISPR/Cas9 KO Plasmid (h2) - sc-407382-KO-2 from Santa Cruz Biotechnology
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DNA pol γ2 HDR Plasmid (h2) - sc-407382-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human POLG2 (NM_007215.3) - SHH379224 from Creative biogene
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Human POLG2 siRNA - orb268200 from Biorbyt
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POLG2 shRNA Plasmid (Human) - CHH7698 from Cohesion Biosciences
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POLG2 miRNA 3'UTR clone - MiUTR3H-07270 from Creative biogene
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