Gene Symbol | KLHDC2 |
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Entrez Gene | 23588 |
Alt Symbol | HCLP-1, HCLP1, LCP |
Species | Human |
Gene Type | protein-coding |
Description | kelch domain containing 2 |
Other Description | hepatocellular carcinoma-associated antigen 33|host cell factor homolog LCP|host cell factor-like protein 1|kelch domain-containing protein 2 |
Swissprots | Q6IAF0 Q86TY9 B3KPF9 Q9Y2U9 |
Accessions | EAW65749 EAW65750 Q9Y2U9 AF113131 AAD21038 AF244137 AAF66246 AK001771 BAA91898 AK056298 BAG51671 BC002335 AAH02335 BC024192 AAH24192 BX161429 CAD61901 CD356831 CF994676 CR457205 CAG33486 DQ895376 ABM86302 EU176349 ABW03800 XM_006720094 XP_006720157 XM_011536610 XP_011534912 NM_014315 NP_055130 |
Function | Represses CREB3-mediated transcription by interfering with CREB3-DNA binding. {ECO:0000269|PubMed:11384994}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11384994}. |
Tissue Specificity | Widely expressed, with high levels in skeletal muscle, heart, pancreas and liver. Undetectable in peripheral blood leukocytes. {ECO:0000269|PubMed:11384994, ECO:0000269|PubMed:16964437}. |
KLHDC2 CRISPR/Cas9 KO Plasmid (h) - sc-411772 from Santa Cruz Biotechnology
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KLHDC2 HDR Plasmid (h) - sc-411772-HDR from Santa Cruz Biotechnology
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KLHDC2 Double Nickase Plasmid (h) - sc-411772-NIC from Santa Cruz Biotechnology
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KLHDC2 Double Nickase Plasmid (h2) - sc-411772-NIC-2 from Santa Cruz Biotechnology
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KLHDC2 CRISPR Activation Plasmid (h) - sc-411772-ACT from Santa Cruz Biotechnology
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KLHDC2 CRISPR Activation Plasmid (h2) - sc-411772-ACT-2 from Santa Cruz Biotechnology
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KLHDC2 Lentiviral Activation Particles (h) - sc-411772-LAC from Santa Cruz Biotechnology
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KLHDC2 Lentiviral Activation Particles (h2) - sc-411772-LAC-2 from Santa Cruz Biotechnology
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KLHDC2 siRNA (h) - sc-92163 from Santa Cruz Biotechnology
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KLHDC2 shRNA Plasmid (h) - sc-92163-SH from Santa Cruz Biotechnology
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KLHDC2 shRNA (h) Lentiviral Particles - sc-92163-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU136621 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11260 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11260 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01444 from Sigma-Aldrich
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KLHDC2 siRNA (Human) - CRH8379 from Cohesion Biosciences
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shRNA set against Human KLHDC2 (NM_014315.2) - SHH325923 from Creative biogene
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shRNA set against Human KLHDC2(NM_014315.2) - SHL200412 from Creative biogene
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Human KLHDC2 siRNA - orb268881 from Biorbyt
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KLHDC2 shRNA Plasmid (Human) - CHH8379 from Cohesion Biosciences
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KLHDC2 miRNA 3'UTR clone - MiUTR1H-05362 from Creative biogene
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