Gene Symbol | ATP5G1 |
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Entrez Gene | 516 |
Alt Symbol | ATP5A, ATP5G |
Species | Human |
Gene Type | protein-coding |
Description | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) |
Other Description | ATP synthase F(0) complex subunit C1, mitochondrial|ATP synthase lipid-binding protein, mitochondrial|ATP synthase proteolipid P1|ATP synthase proton-transporting mitochondrial F(0) complex subunit C1|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9)|ATPase protein 9|ATPase subunit 9|ATPase subunit C|mitochondrial ATP synthase, subunit 9|mitochondrial ATP synthase, subunit C |
Swissprots | P05496 |
Accessions | CAA49532 EAW94705 EAW94706 P05496 AK095669 AK311848 BAG34790 AL080089 CAB45704 AM393437 CAL38315 BC004963 AAH04963 BF573360 BG611396 BT007230 AAP35894 BU596803 CF129854 CR533449 CAG38480 D13118 BAA02420 M16453 AAA51806 NM_001002027 NP_001002027 NM_005175 NP_005166 |
Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element. |
Subcellular Location | Mitochondrion membrane; Multi-pass membrane protein. |
Top Pathways | Alzheimer's disease, Huntington's disease, Oxidative phosphorylation |
ATP5G1 CRISPR/Cas9 KO Plasmid (h) - sc-416816 from Santa Cruz Biotechnology
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ATP5G1 HDR Plasmid (h) - sc-416816-HDR from Santa Cruz Biotechnology
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ATP5G1 Double Nickase Plasmid (h) - sc-416816-NIC from Santa Cruz Biotechnology
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ATP5G1 Double Nickase Plasmid (h2) - sc-416816-NIC-2 from Santa Cruz Biotechnology
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ATP5G1 CRISPR Activation Plasmid (h) - sc-416816-ACT from Santa Cruz Biotechnology
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ATP5G1 CRISPR Activation Plasmid (h2) - sc-416816-ACT-2 from Santa Cruz Biotechnology
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ATP5G1 Lentiviral Activation Particles (h) - sc-416816-LAC from Santa Cruz Biotechnology
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ATP5G1 Lentiviral Activation Particles (h2) - sc-416816-LAC-2 from Santa Cruz Biotechnology
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ATP5G1 siRNA (h) - sc-93700 from Santa Cruz Biotechnology
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ATP5G1 shRNA Plasmid (h) - sc-93700-SH from Santa Cruz Biotechnology
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ATP5G1 shRNA (h) Lentiviral Particles - sc-93700-V from Santa Cruz Biotechnology
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ATP synthase C mature RNAi - H00000516-R01 from Novus Biologicals
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MISSION® esiRNA - EHU113661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3701 from Sigma-Aldrich
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ATP5G1 siRNA (Human) - CRH0357 from Cohesion Biosciences
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ATP synthase C mature RNAi - H00000516-R02 from Novus Biologicals
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ATP5G1 - MBS8204469 from MyBioSource
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shRNA set against Human ATP5G1 (NM_005175.2) - SHH242806 from Creative biogene
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shRNA set against Human ATP5G1(NM_001002027.1) - SHG082423 from Creative biogene
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Human ATP5G1 siRNA - orb260859 from Biorbyt
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ATP5G1 shRNA Plasmid (Human) - CHH0357 from Cohesion Biosciences
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ATP5G1 miRNA 3'UTR clone - MiUTR1H-00696 from Creative biogene
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ATP5G1 miRNA 3'UTR clone - MiUTR3H-05764 from Creative biogene
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