Gene Symbol | ATF5 |
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Entrez Gene | 22809 |
Alt Symbol | ATFX, HMFN0395 |
Species | Human |
Gene Type | protein-coding |
Description | activating transcription factor 5 |
Other Description | cAMP-dependent transcription factor ATF-5|cyclic AMP-dependent transcription factor ATF-5|transcription factor ATFx |
Swissprots | Q9UNQ3 Q9Y2D1 B3KND3 Q9BSA1 |
Accessions | CAC34908 CAE92201 EAW52581 EAW52582 EAW52583 Q9Y2D1 AB021663 BAA78477 AB073613 BAD38650 AF101388 AAD28370 AF305687 AAG22558 AK024402 BAG51295 AK091985 AK290592 BAF83281 BC005174 AAH05174 BF528888 BM462249 BP378116 BU187153 BU730542 DA251296 DA684664 HY011917 XM_011526629 XP_011524931 NM_001193646 NP_001180575 NM_001290746 NP_001277675 NM_012068 NP_036200 |
Function | Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4. {ECO:0000269|PubMed:10373550, ECO:0000269|PubMed:15358120}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15358120}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:15358120}. |
ATF-5 CRISPR/Cas9 KO Plasmid (h) - sc-416821 from Santa Cruz Biotechnology
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ATF-5 HDR Plasmid (h) - sc-416821-HDR from Santa Cruz Biotechnology
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ATF-5 Double Nickase Plasmid (h) - sc-416821-NIC from Santa Cruz Biotechnology
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ATF-5 Double Nickase Plasmid (h2) - sc-416821-NIC-2 from Santa Cruz Biotechnology
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ATF-5 CRISPR Activation Plasmid (h) - sc-416821-ACT from Santa Cruz Biotechnology
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ATF-5 CRISPR Activation Plasmid (h2) - sc-416821-ACT-2 from Santa Cruz Biotechnology
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ATF-5 Lentiviral Activation Particles (h) - sc-416821-LAC from Santa Cruz Biotechnology
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ATF-5 Lentiviral Activation Particles (h2) - sc-416821-LAC-2 from Santa Cruz Biotechnology
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ATF-5 siRNA (h) - sc-43580 from Santa Cruz Biotechnology
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ATF-5 shRNA Plasmid (h) - sc-43580-SH from Santa Cruz Biotechnology
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ATF-5 shRNA (h) Lentiviral Particles - sc-43580-V from Santa Cruz Biotechnology
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ATF5 RNAi - H00022809-R01 from Novus Biologicals
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MISSION® esiRNA - EHU039491 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1337 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1337 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06430 from Sigma-Aldrich
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ATF5 siRNA (Human) - CRH7786 from Cohesion Biosciences
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ATF5 - MBS8214534 from MyBioSource
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shRNA set against Human ATF5 (NM_012068.5) - SHH241942 from Creative biogene
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Human ATF5 siRNA - orb268288 from Biorbyt
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ATF5 shRNA Plasmid (Human) - CHH7786 from Cohesion Biosciences
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ATF5 miRNA 3'UTR clone - MiUTR3H-08421 from Creative biogene
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